“…Resolution is increased by dispersing signals into a second frequency dimension, but additional time is required to sample this dimension -several hours where high digital resolution is required to overcome signal overlap. 2D pure shift NMR experiments [5][6][7][8] can reduce the time needed to sample the second dimension by suppressing signal multiplicity. These methods provide clear and simple correlations, but reduce the chemical information content of the spectrum, and almost always incur a sensitivity penalty.…”
Selective 1D COSY can unambiguously identify coupled spins but is often limited both by lack of selectivity, and by unfavourable multiplet lineshapes. Here, ultra selective GEMSTONE excitation is employed with...
“…Resolution is increased by dispersing signals into a second frequency dimension, but additional time is required to sample this dimension -several hours where high digital resolution is required to overcome signal overlap. 2D pure shift NMR experiments [5][6][7][8] can reduce the time needed to sample the second dimension by suppressing signal multiplicity. These methods provide clear and simple correlations, but reduce the chemical information content of the spectrum, and almost always incur a sensitivity penalty.…”
Selective 1D COSY can unambiguously identify coupled spins but is often limited both by lack of selectivity, and by unfavourable multiplet lineshapes. Here, ultra selective GEMSTONE excitation is employed with...
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