Punctal stenosis in 6 dogs following the long‐term use of topical neomycin‐polymyxin B‐dexamethasone

Abstract

Six dogs were diagnosed with punctal stenosis following the long-term use of topical neomycin-polymyxin B-dexamethasone (NPD). All patients were initially presented for ophthalmic diseases requiring ongoing anti-inflammatory therapy. Five of the 6 dogs had previously or concurrently been treated with topical anti-inflammatory medications other than NPD. One patient exclusively received topical NPD prior to the diagnosis of punctal stenosis. The onset of punctal stenosis following therapy with NPD was variable among patients, ranging from 4 months to over 1 year. Diagnosis of punctal stenosis was made based upon the presence of epiphora and visualization of fibrotic tissue over the nasolacrimal puncta.

Evaluation of the upper and lower proximal lacrimal canaliculi using spectral‐domain optical coherence tomography in normal Beagle dogs

“…Considering the superficial location of the LC, ultrasound biomicroscopy (UBM) is frequently used to visualize the structure 3,5,6 . However, the limitations of UBM are poor resolution images and contact with the examination site 7–9 .…”

“…3,4 Considering the superficial location of the LC, ultrasound biomicroscopy (UBM) is frequently used to visualize the structure. 3,5,6 However, the limitations of UBM are poor resolution images and contact with the examination site. [7][8][9] Alternatively, the LC has been imaged using lacrimal scintigraphy, computed tomography dacryocystography, and magnetic resonance imaging in human medicine.…”