Pump-driven haemofiltration

Continuous Renal Replacement Therapies (CRRT) Overview

“…However, these techniques could not overcome the disadvantages inherent to an arteriovenous (AV) circuit including dependence of blood flow on the pressure gradient between mean arterial pressure and central venous pressure, which limited flow, particularly in hypotensive and hemodynamically unstable patients, and complications related to prolonged arterial cannulation, including bleeding, thromboembolism, and infection. These inherent problems with the AV circuit led to the development of pumped venovenous (VV) systems [16][17][18]. The use of a VV circuit, however, sacrificed the technical simplicity of the AV system, necessitating the addition of air detectors and pressure monitors.…”