Pulsed source time resolved phosphorimetry for the quantitative and qualitative analysis of drugs

Kf, Harbaugh; Cm, O'Donnell; Jd, Winefordner

doi:10.1021/ac60345a045

Cited by 42 publications

(18 citation statements)

References 17 publications

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“…Since then, phosphorimetry has gradually gained general acceptance as an analytical tool of merit. A number of publications in this area readily confirms this observation (3)(4)(5)(6). The routine detection of room-temperature phosphorescence in diverse matrices (7)(8)(9)(10) is now lending further impetus to development of a wider range of applications for phosphorimetry.…”

mentioning

confidence: 64%

“…Using similar notation, one can define a standard EEM for the feth component N* = akoxk ykT (3) of the mixture matrix M,= L«w'Nfc (4) k=i where aki = aki/ako (5) For ratio deconvolution (19) of an r-component mixture, one needs a set of "r" EEMs, i.e., a series of M; for l = 0, 1, 2,..., r -I. Thus, one can obtain a set of "r" matrices, each of which contains a maximum of only "r" emitters.…”

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confidence: 99%

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Multicomponent mixture analysis by multidimensional phosphorimetry

Ho¹,

Warner²

1982

Anal. Chem.

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A technique based on the rapid scanning capability of the video fluorometer to acquire an emission-excitation matrix (EEM) has been developed for phosphorimetry. This technique overcomes the problem of convolution of time decay with phosphorescence excitation and emission spectra by integrating the signal on target. This method also circumvents the need for very rapid acquisition of data for samples with phosphors of very short lifetimes. A phosphorescence emission-excitation matrix (PEEM) obtained in this manner permits time resolution. Sets of each tlme-PEEM allow a ratio deconvolution algorithm to successfully resolve mixtures of polynuclear aromatic compounds.

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confidence: 64%

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confidence: 99%

Multicomponent mixture analysis by multidimensional phosphorimetry

Ho¹,

Warner²

1982

Anal. Chem.

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“…For more difficult analytical problems substantially increased component discrimination could be readily provided by utilizing time-resolved phosphorimetry (2,10,32,37). As an example of the potential usefulness of time-resolution, the selectively excited LIP spectrum of 1,4-DBN in the 10-component mixture is illustrated by Figure 4a, while the timeresolved spectrum is depicted in Figure 4b.…”

Section: Resultsmentioning

confidence: 99%

Laser-induced phosphorescence spectrometry of halogenated naphthalene derivatives prepared in vapor-deposited parent molecule matrices

Pace¹,

Maple²

1989

Anal. Chem.

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“…Sawicki was able to characterize very complex mixtures of polycyclic aromatic hydrocarbons for molecules containing the fluoranthenic-type ring system. Lloyd (4) used plots of the Stern-Volmer relationship resulting from the variation of quencher concentration and synchronously excited fluorescence for the characterization of engine oils and other complex mixtures for benzo[a]pyrene and other polycyclic aromatic hydrocarbons. Zander (5) has studied the fluorescence quenching of polycyclic aromatic hydrocarbons in a benzene/methyl iodine mixture.…”

Section: Resultsmentioning

confidence: 99%