Pulse anodic stripping voltammetric determination of copper with an amoxicillin–nafion modified glassy carbon electrode

Abstract

The analysis of Cu 2+ by pulse anodic stripping voltammetry using a Nafion-modified glassy Carbon electrode incorporated with Amoxicillin is described. A significant increase in the voltammetric response was achieved at the modified electrode compared to a bare glassy carbon electrode. Cu 2+ was accumulated in HAcNaAc buffer (pH 3.6) at a potential of -0.7 V (vs. Ag/ AgCl) for a certain time and then determined by pulse anodic stripping voltammetry. Parameters and conditions, such as the mass of Nafion, the concentration of Amoxicillin, the pH of medium, the accumulation potential, and the accumulation time were optimized. Under the optimum conditions, the calibration curve was linear in the range 8 9 10 -10 -2 9 10 -8 M with a correlation coefficient of 0.9998 and relative standard deviation 4.87% (n = 5). The detection limit was 1.3 9 10 -10 M. A study of interfering substances was also performed and the analytical utility of the method was demonstrated by applying to various pharmaceutical products.

Square Wave‐Anodic Stripping Voltammetric Determination of Copper at a Bismuth Film/Glassy Carbon Electrode Using 3‐[(2‐Mercapto‐Vinyl)‐Hydrazono]‐ 1,3‐Dihydro‐Indol‐2‐One

“…Thus, the developed method is simple, accurate, low cost approach with short deposition time for copper determination. The analytical features of the proposed SW‐ASV procedure were satisfactorily compared with many electrochemical methods as demonstrated in Table . The figure merits for the developed method confirms the suitability of the present method to be utilized for routine analysis of copper in different samples.…”

“…The surface coverage of the electroactive species (Γ) was calculated from their CVs at the bare GCE using the equation : …”

“…The most common practice utilized is the enhancement of selectivity towards host and target . Based on the principle, electrode modification by a series of reagents including amoxicillin , hexacyanoferrate , tetraethylthiuram disulfide , tetraphenylporphyrin , p‐tert‐butylcalix(4)arene , organofunctionalized silica and nafion have been reported for copper determination.…”