Pulsatile ocular blood flow changes after panretinal photocoagulation treatment in patients with proliferative diabetic retinopathy

Abstract

Although for ultrabasic and basic magmas a plethora of tectonomagmatic diagrams have been used, with the exception of one bivariate diagram for refined tectonic setting of orogenic andesites, none is available for highly abundant intermediate magma.We present 3 sets of discrimination diagrams obtained from the correct statistical methodology of log e -ratio transformation and linear discriminant analysis. All major element log e -ratio variables in 3664 samples, only immobile major and trace element log e -ratio variables in 1858 samples, and immobile trace element log e -ratio variables in 1512 samples were used. These diagrams with probability-based tectonic field boundaries and high success rates (about 69%-96%, 63%-100%, and 64%-100%, respectively, for diagrams based on all major elements, immobile major and trace elements, and immobile trace elements) were first tested for fresh and highly altered rocks. The expected tectonic setting was indicated from our diagrams. The probability-based decisions and total percent probability estimates can fully replace the actual plotting of samples in the diagrams. The probability calculations were then used for tectonic discrimination of 7 case studies of Archean to Proterozoic rocks. An island arc setting was indicated for the Wawa greenstone belt (Canada), implying the existence of plate tectonic processes during the Late Archean, for western Tasmania (Australia) during the Cambrian, and for Chichijima Island (Bonin Islands, Japan) during the Eocene. Similarly, an arc setting (indecisive island or continental type) was obtained for south-central Sweden during the Paleoproterozoic and for Adola (southern Ethiopia) during the Neoproterozoic. A within-plate setting was inferred for the Neoproterozoic Malani igneous complex, Rajasthan, India. A collision setting was indicated for the Alps (France-Italy-Switzerland) during the Late Carboniferous. Modeling of likely as well as extreme processes indicates that these diagrams are robust against postemplacement compositional changes caused by analytical errors, element mobility, Fe-oxidation, alteration, and petrogenetic processes.

Ocular Pulse Amplitude after Panretinal Photocoagulation in Normotensive Eyes with Proliferative Diabetic Retinopathy

“…Exclusion criteria included (1) previous laser treatments; (2) prior vitreoretinal surgery (vitrectomy, intravitreal triamcinolone injection) in the study eye; (3) history of any thromboembolic event (including myocardial infarction or cerebral vascular accident); (4) major surgery within the prior 6 months; (5) glaucoma under treatment or elevated IOP (above 21 mm Hg Goldmann applanation tonometry); (6) known coagulation abnormalities or current use of anticoagulant medication other than aspirin; (7) evidence of external ocular infection (conjunctivitis, keratitis, or significant blepharitis); (8) refractive error ±3.0 SD; (9) history of antihypertensive medication use.…”

“…The gold standard treatment for proliferative diabetic retinopathy treatment is panretinal laser photocoagulation. The impact of panretinal photocoagulation (PRP) on intraocular pressure (IOP) levels has been studied before (1)(2)(3) but the effect of PRP on ocular pulse amplitude (OPA) has rarely been the focus of reported investigations.…”

Risk Factors and Management of Intraocular Pressure Elevation After Vitrectomy Combined with Silicone Oil Tamponade

“…This observation raises speculations that PRP exacerbates the postoperative inflammatory response, interferes with venous blood reflux in the choroid, and induces changes in local hemodynamics and opening of the capillary bed. These factors contribute to choroidal and ciliary body edema and exudation, 59 as well as forward movement of the iris root, narrowing of the anterior chamber angle, obstruction of aqueous humor outflow pathways, and subsequent elevation of intraocular pressure. 60 , 61 Meanwhile, the study 45 also found that patients undergoing membrane segmentation during surgery appear to have a lower risk of increased intraocular pressure.…”