Pulpal Remineralisation of Artificial Residual Caries Lesions in vitro

Schwendicke, Falk; Al-Abdi, Allam; Meyer-Lückel, Hendrik; Paris, Sebastian

doi:10.1159/000440906

Cited by 4 publications

(7 citation statements)

References 19 publications

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“…A number of clinical studies confirmed mineral gain and dentin re-hardening in teeth restored without remineralizing material, postulating that any kind of mineral is needed to be provided by the dental pulp [20,32,36]. That could theoretically mean that cavity liners or remineralizing restoration materials are not needed.…”

Section: Discussionmentioning

confidence: 99%

“…Mineral content (in vol%) was determined via microradiography (right y-axis) and is exemplarily shown for one GH sample (solid orange line) and CO sample (dotted yellow line). Note that mineral loss was assessed only for the coronal 2/3, not the full thickness of the dentin disc implemented for simulating possible pulpal effects in vitro [14,32,37]. The present study employed such system and investigated the mineral gains provided by the simulated pulp in comparison with those from different materials.…”

Section: Discussionmentioning

confidence: 99%

“…It remains unclear, however, if such recharge is provided to superficial material layers only or if fluoride transport into those layers relevant for remineralization of dentin is truly occurring. Pulpally, a protein-containing simulated pulpal fluid was supplied, which was supersaturated for minerals and has been shown to provide remineralization to sealed lesions if sufficient pressure is applied [32]. It is unclear if this fluid truly mimics pulpal fluid effects, and in vivo, pulpal pressure might vary individually or according to pulpal health.…”

Section: Discussionmentioning

confidence: 99%

“…Discs were then fitted into the lit of a custom-made dualchamber system, with pulpal and coronal surfaces exposed two different chambers [32]. The coronal chamber was filled with defined mucine medium (DMM) to simulate the oral milieu [33].…”

Section: Pulpal Fluid Simulation Systemmentioning

confidence: 99%

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Glass hybrid, but not calcium hydroxide, remineralized artificial residual caries lesions in vitro

2016

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Pulpal Fluid Simulation Systemmentioning

confidence: 99%

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Glass hybrid, but not calcium hydroxide, remineralized artificial residual caries lesions in vitro

2016

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“…[162129] This article provided evidence that dentin reorganization and mineral changes were not dependent on the material placed in contact with the carious tissue, suggesting that the carious arrestment is a host-driven process rather than a material-induced process. [30]…”

Section: Discussionmentioning

confidence: 99%

The influence of the lining material on the repair of the infected dentin in young permanent molars after restoration: A randomized clinical trial

et al. 2016

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Aim:This study evaluated the impact of liner material on the fluorescence, morphological and mineral characteristics of permanent carious dentin after cavity sealing.Methods:Thirty children (11.0 ± 2.7 years old) presenting at least one active deep carious lesion in permanent molars were selected. Fragments of carious dentin were removed from teeth before lining the cavity (baseline samples) with high-viscosity glass ionomer cement (G1) or an inert material (wax - G2). Cavities were restored with composite resin and reopened 60 days later, and other fragments were removed (60-day sample). The laser fluorescence (LF) readings and morphological and mineral changes of both groups were compared.Results:After 60 days, forty teeth were available for evaluation. Lower LF means were obtained (Wilcoxon signed-rank test; P < 0.05), and enhanced calcium and phosphorus levels were detected for both groups (t-test, P < 0.05). An uptake of fluorine was observed only in G1 (t-test; P < 0.05). Regardless of the group, baseline samples exhibited clear signs of bacterial invasion, and the collagen fibers were exposed; the 60-day samples showed a better-organized tissue with a more compact intertubular dentin.Conclusion:Caries arrestment with dentin reorganization occurs regardless of the lining material placed in contact with the infected dentin.

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In vitroRemineralization of Caries-affected Dentin after Selective Carious Tissue Removal

Ali¹,

Almaroof²,

Festy³

et al. 2018

World Journal of Dentistry

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Aim: This study aimed to evaluate the mineral deposition and microhardness within the retained caries-affected dentin (CAD) after excavation with Carisolv™ gel or rotary burs. Materials and methods:Totally 20 extracted human carious molars, with caries extending into the middle third of dentin, were sectioned mesiodistally. The carious tissue in each hemi-section was excavated with gel or bur and restored with a mineral trioxide aggregate (MTA) base and resin composite. Five sound posterior teeth were hemi-sected to serve as a control. Twenty-five hemi-sections were stored in distilled water (DW) and the other 25 were stored in simulated body fluid (SBF). Each sample was scanned and tested using Raman spectroscopy and Knoop microhardness respectively, at the MTA-dentin interface at day 1 and 14. Scanning electron microscope (SEM) was used to assess the surface topography of dentin after excavation with gel/bur. Results:The results show that the baseline mineral content and microhardness of dentin were significantly lower in Carisolv™treated samples in comparison with that treated with burs (p ≤ 0.05). However, there were comparable mineral levels in the two groups after 14 days' storage in SBF (p ≥ 0.05), which showed statistically insignificant differences from the sound control (p ≥ 0.05). Microhardness and mineral contents decreased significantly in the sound control after 14 days' storage in DW (p ≤ 0.05). The SEM images showed partially open dentin tubules with less smear layer after Carisolv™ excavation compared with more occluded dentin tubules with an abundance of smear layer after bur excavation. Conclusion:Although gel excavation retains more CAD in comparison with bur, remineralization of this remaining tissue is evident after 2 weeks. Clinical significance:The use of Carisolv™ gel provides an alternative to rotary burs in terms of preserving the tooth structure and not hindering the remineralization potential of valuable tooth structure, a clinical advantage for minimally invasive dentistry.

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Pulpal Remineralisation of Artificial Residual Caries Lesions in vitro

Cited by 4 publications

References 19 publications

Glass hybrid, but not calcium hydroxide, remineralized artificial residual caries lesions in vitro

Glass hybrid, but not calcium hydroxide, remineralized artificial residual caries lesions in vitro

The influence of the lining material on the repair of the infected dentin in young permanent molars after restoration: A randomized clinical trial

In vitroRemineralization of Caries-affected Dentin after Selective Carious Tissue Removal

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