Pulmonary tuberculosis presenting as diffuse cystic lung disease: An atypical manifestation

Kodati, Rakesh; Tadepalli, Anuradha; Reddy, C Mallikarjuna

doi:10.1016/j.ijtb.2019.11.016

Cited by 6 publications

(5 citation statements)

References 6 publications

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“…In the Indian subcontinent, pulmonary tuberculosis is an important consideration. [4,5] However, sporadic LAM has been documented with few case reports describing males and children presenting with this condition and should always be considered. [6] The typical clinical symptoms of LAM in men, such as cough, breathlessness, and hemoptysis, are similar to those observed in most women with the condition.…”

Section: Discussionmentioning

confidence: 99%

Spontaneous pneumothorax in a young male: A case report

Kudru,

Rajagopal,

Cherukuri

et al. 2024

Preprint

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Background: Pulmonary lymphangioleiomyomatosis is a rare multisystem disease which is characterised by the development of multiple cysts in the lung parenchyma. It is usually associated with tuberous sclerosis complex, and is frequently found in young females. In our case report, we discuss the disease in a young male, presenting for the first time with spontaneous pneumothorax. Case presentation: A 19-year-old previously healthy male presented to the emergency department with a one week history of breathlessness and a non-productive cough. Initial assessment revealed tachypnea and decreased breath sounds on the right side of the chest, prompting suspicion of pneumothorax. The chest x-ray confirmed the diagnosis, and emergency insertion of an intercostal drainage tube was performed. Computed tomography of the thorax showed multiple, bilateral, cystic, thin walled lesions and a moderate pneumothorax on the right side. A lung biopsy was performed and the histopathology revealed features consistent with lymphangioleiomyomatosis (LAM). The patient was stabilized and discharged with follow-up plans. Conclusions: LAM is a rare multisystem disease that mostly affects young females. Although uncommon in males, this case emphasizes the importance of considering LAM as one of the causes of pneumothorax in young adult male patients and highlights the role of lung biopsy for definitive diagnosis when initial workup is inconclusive.

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Section: Discussionmentioning

confidence: 99%

Spontaneous pneumothorax in a young male: A case report

Kudru,

Rajagopal,

Cherukuri

et al. 2024

Preprint

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“…If the treatment is not timely, it will seriously affect their physical and mental health [ 14 ]. In recent years, due to the extensive use of antibiotics, the drug resistance of Mycobacterium tuberculosis has been increasing, and the efficacy of drugs has become more and more limited [ 15 ]. Patients with pulmonary tuberculosis generally have low immunity.…”

Section: Discussionmentioning

confidence: 99%

Intelligence Classification Algorithm-Based Drug-Resistant Pulmonary Tuberculosis Computed Tomography Imaging Features and Influencing Factors

Jiang

Zhao

Fan

2022

Computational Intelligence and Neuroscience

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The drug resistance and influencing factors of patients with pulmonary tuberculosis were investigated, and a dual attention dilated residual network (DADRN) algorithm was proposed. The algorithm was applied to process and analyze lung computed tomography (CT) images of 400 included patients with pulmonary tuberculosis. Besides, sparse code book algorithm and bag of visual word (BOVW) algorithms were introduced and compared, and the influencing factors of pulmonary tuberculosis drug resistance were analyzed. The results demonstrated that the localization precision of lung consolidation, nodules, and cavities by the DADRN algorithm reached 91.2%, 92.5%, and 93.8%, respectively. The recall rate of the three algorithms amounted to 83.55%, 84.5%, and 86.4%, respectively. Both localization precision and recall rate of the DADRN algorithm were higher than those of other two algorithms ( P < 0.05 ). The drug resistance rate of streptomycin, isoniazid, and rifampin of the patients aged between 40 and 59 was all higher than those of the patients in other age groups. The drug resistance rate of streptomycin, isoniazid, and rifampin of retreated patients was all higher than those of patients initially treated. The drug resistance rate of streptomycin, isoniazid, and rifampin of the patients with tuberculosis contact was all higher than those of the patients without tuberculosis contact ( P < 0.05 ). Based on the above results, the accuracy of CT images processed by dual attention-based dilated residual classification network algorithm was higher than that processed by other two algorithms. Age, medical history, and history of exposure to tuberculosis were the influencing factors of the drug resistance of patients with pulmonary tuberculosis.

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“…Signs and symptoms of infection often involve shortness of breath, cough, hemoptysis and muscle weakness, and a number of which our patient ridden from before his death. (Kodati, Tadepalli, Chandana, 2019).…”

Section: Discussionmentioning

confidence: 99%

Health Related Quality of Life and It's Association With Medication Adherence for Patients With Pulmonary Tuberculosis

Omar

Bakr

Sobeh

et al. 2020

Port Said Scientific Journal of Nursing

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Background: Tuberculosis (TB) has been ranked to be one of the top ten causes of global mortality worldwide. The concept of health-related quality of life (HRQOL) might be of a multi-dimensional nature, it includes psychological, physical and social aspects. The effectiveness of medical interventions is influenced by adherence. Aim: This study aims to assess the correlation between health related quality of life (HRQOL) and medication adherence for Patients with pulmonary tuberculosis. Subjects and Method: A design based on descriptive correlational research was utilized. Convenient sample of pulmonary tuberculosis patients (56) at Almasaha Albahary at Port Said City and Chest Hospital at Damietta City. Three structured interviews were utilized to gather the required data. Data collection tools: Tool I: structured interviewing questionnaire, Tool II: Health Related Quality of life for patients with chronic illness, Tool III: Morisky Medication Adherence Scale (MMAS-8). Results: this study showed that 67.9% of the subjects were high psychological domain of health related quality of life and moreover, 75% of them were highly adhered to medications. Conclusion: it can conclude that three fifth of the studied patients had high QOL and three quarters of the patients had high adherence to medication. This study showed that there was statistically positive correlation between HRQOL domains (Physical, psychological, social) of HRQOL and drug adherence. Recommendation: the study recommended the event of program for patients with TB to enhance the patients' knowledge, care management and modify their wrong beliefs associated with TB.

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Pulmonary tuberculosis presenting as diffuse cystic lung disease: An atypical manifestation

Cited by 6 publications

References 6 publications

Spontaneous pneumothorax in a young male: A case report

Spontaneous pneumothorax in a young male: A case report

Intelligence Classification Algorithm-Based Drug-Resistant Pulmonary Tuberculosis Computed Tomography Imaging Features and Influencing Factors

Health Related Quality of Life and It's Association With Medication Adherence for Patients With Pulmonary Tuberculosis

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