Pulmonary tuberculosis among people living with HIV/AIDS attending care and treatment in rural northern Tanzania

Ngowi, Bernard; Mfinanga, Sayoki; Bruun, Johan N.; Mørkve, Odd

doi:10.1186/1471-2458-8-341

Cited by 60 publications

(65 citation statements)

References 14 publications

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“…Lower cumulative incidence might due to improved TB/HIV chronic care and introduction of new regimen which effectively prevent occurrence of TB among HIV. Overall cumulative density reported in this study was lower than studies done in many other Sub Sahara African countries including, Ethiopia with reported incidence rate ranging from 5.4 to 11 per 100 PY [25]- [28]. Lower incidence rate could be explained by improved TB/HIV Care and new introduction of regimen which effectively prevent occurrence of TB among HIV.…”

Section: Discussioncontrasting

confidence: 52%

Incidence and Predictors of Tuberculosis among HIV/AIDS Infected Patients: A Five-Year Retrospective Follow-Up Study

Dalbo¹,

Tamiso²

2016

AID

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Background: Despite increased deliverance of antiretroviral therapy (ART), morbidity and mortality from TB are still predominant among HIV/AIDS infected patients in Ethiopia. Thus, current study aimed to determine magnitude and predictors of tuberculosis among cohort of HIV infected patients at Arba Minch General Hospital, Ethiopia, 2015. Methods: Hospital based retrospective follow-up study was conducted among study population which was HIV/AIDS infected individuals registered from September 2007 to 2013. The data were collected using structured data abstraction form and four ART trained nurses were used to abstract the data. The data were checked for completeness, cleaned and entered into Epi Info 7.0 and analyzed using SPSS version (IBM-21). Results were summarized by using table of frequency, graph, and measure of central tendency. Statistical significance was inferred at P-value ≤ 0.05. Adjusted odd ratio (AOR) with 95% confidence interval (CI) was used to determine predictors. Result: Four hundred ninety six patient's charts were abstracted. Cumulative and incidence density of tuberculosis were 21.4% (95% CI: 21.3, 21.44) and 5.36 per 100 person year respectively. Cigarette smokers (AOR: 2.82, 95% CI (1.27 -6.27)), household with family size of 3 -4 (AOR: 2.26, 95% CI (1.14 -4.50)), baseline WHO clinical stage III (AOR: 20.26, 95% CI (7.09 -57.6)) and IV (AOR: 22.9, 95% CI (6.91 -76.4)) and heamoglobin level of <10 (AOR: 2.56, 95% CI (1.22 -5.33)) were important predictors (risk factors) of tuberculosis among HIV infected patients. Conclusion and recommendation: Relatively high incident tuberculosis cases were established among HIV infected patients and history of cigarette smoking; family size; hemoglobin level and base line WHO clinical stage were responsible for this incidence. Therefore; early initiation of HAART as per current guideline should get stressed, and the finding that smoking was important predictors for TB in Ethiopia had obvious TB control implication which required high attention focused on fighting against cigarette smoking among HIV infected cohort.

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Section: Discussioncontrasting

confidence: 52%

Incidence and Predictors of Tuberculosis among HIV/AIDS Infected Patients: A Five-Year Retrospective Follow-Up Study

Dalbo¹,

Tamiso²

2016

AID

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“…This finding was in line with studies conducted in India (17%), Nigeria (16.8%, 14.4%, 9.6% [1][2][3][4]. However, relatively higher prevalence has been reported from Nepal (27.3%) and Nigeria (22.7%) [5,6], and lower results were reported from Northern Tanzania (8.3%) [7]. Slight variation on the magnitude of tuberculosis in HIV/AIDS patients may be due to differences of HIV infection rate in the population, TB-diagnostic facilities available, health care awareness of the community to seek health care for both TB and HIV.…”

Section: Discussionsupporting

confidence: 39%

“…For instance, an observational community-based ART cohort study conducted in South Africa to show shortterm and long-term risk of tuberculosis associated with CD4 cells recovery during antiretroviral therapy revealed that unadjusted TB incidence rates were 16.8, 9.3, 5.5, 4.6, 4.2 and 1.5 cases/100 person-years, respectively (P < 0.001) [14], during person-time accrued within CD4 cell strata 0-100, 101-200, 201-300, 301-400, 401-500 and more than 500 cells/μl. Similarly, low level of CD4 count was reported as risk factor for development of tuberculosis in HIV/AIDS patients from Tanzania [7] and Ethiopia [8][9][10].…”

Section: Discussionmentioning

confidence: 99%

Prevalence and determinants of Tuberculosis among HIV infected patients in south Ethiopia

Fekadu

Teshome

Alemu

2015

J Infect Dev Ctries

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Introduction: Tuberculosis (TB) is a chronic infectious disease that has represented a major health problem over the centuries. The human immune deficiency virus (HIV)/AIDS has substantially altered the epidemiology of TB by increasing the risk of reactivating latent TB, increasing chance of TB infection once exposed to tubercle bacilli (re-infection) and by increasing the risk of rapid progression soon after infection. Methodology: This study employs a retrospective review analysis of patient medical records. A total of 499 HIV/AIDS patient cards were reviewed and variables were recorded. Frequencies and odds ratio were calculated to determine prevalence and associated risk factors respectively. Results: A total of 499 HIV/AIDS positive patient cards were reviewed. Ninety one (18.2%) of the study participants were found to have tuberculosis of which 20 (22%), 58 (64%) and 13 (14%) were smear positive, smear negative and extra-pulmonary tuberculosis cases, respectively. In multivariate logistic regression being female (AOR=0.

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“…These results are almost equal to Bernard J Ngowi et al's fi ndings which shows the same prevalence as 45.0% and 30.0% in the age group of 25 to 34 years and 35 to 49 years respectively. 34 Yadav DK et al revealed that 60% of TB/HIV co-infected belonged to the age group (31-40) years, while 35.7% of subjects was belonged to age group (21)(22)(23)(24)(25)(26)(27)(28)(29)(30) years. 33 Mansoori D et al revealed that 64% of TB/ HIV infected patients were 20-40 years old and 36% were 41 years old or more.…”

mentioning

confidence: 99%

Prevalence Of Tuberculosis Among Hiv Positive Patients Attending Ictc In A Tertiary Care Institute In Ahmadabad, A Western City Of India

Nayak

Karia

Patel

et al. 2013

SAARC J. Tuber. Lung Dis. HIV/AIDS

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Pulmonary tuberculosis among people living with HIV/AIDS attending care and treatment in rural northern Tanzania

Cited by 60 publications

References 14 publications

Incidence and Predictors of Tuberculosis among HIV/AIDS Infected Patients: A Five-Year Retrospective Follow-Up Study

Incidence and Predictors of Tuberculosis among HIV/AIDS Infected Patients: A Five-Year Retrospective Follow-Up Study

Prevalence and determinants of Tuberculosis among HIV infected patients in south Ethiopia

Prevalence Of Tuberculosis Among Hiv Positive Patients Attending Ictc In A Tertiary Care Institute In Ahmadabad, A Western City Of India

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