Pulmonary Strongyloides stercoralis infection

Abstract

The 17-year-old male patient presented with fever, weakness, dyspnea and weight loss. His chest radiography demonstrated diffuse reticulonodular density, and high-resolution lung tomography indicated diffuse micronodules and prevalent ground-glass pattern. The findings were consistent with miliary involvement. The patient underwent examinations for rheumatology, immunology, cytology and infectious conditions. His immune system was normal and had no comorbidities or any history of immunosuppressive treatment. Strongyloides stercoralis larvae were noted upon direct inspection of the feces. Clinical and radiological improvement was achieved with albendazole 400 mg/day. This case is being presented since miliary involvement in the lungs caused by S. stercoralis infection in an individual with intact immune system is rare and difficult to diagnosis.

Severe Anemia and Lung Nodule in an Immunocompetent Adopted Girl with Strongyloides stercoralis Infection

“…Nodular pulmonary lesions caused by S. stercoralis have been rarely reported too, and in particular, there is no information on their frequency in asymptomatic patients. 10,11 They might derive from the migration of the larvae to the lungs, as suggested by Dogan and others, who found granulomas surrounding S. stercoralis larvae in the histological examination of lung biopsies performed in a patient. 10 We prescribed a chest X-ray for a general assessment of the patient, in absence of respiratory complaints.…”

“…10,11 They might derive from the migration of the larvae to the lungs, as suggested by Dogan and others, who found granulomas surrounding S. stercoralis larvae in the histological examination of lung biopsies performed in a patient. 10 We prescribed a chest X-ray for a general assessment of the patient, in absence of respiratory complaints. In our experience (and in line with other experts' opinion 12 ), invasive procedures (such as pulmonary biopsy) can be avoided in the first assessment of a lung nodule in a patient with a parasitic infection, in particular, if the index of suspicion for other severe conditions is low.…”

Strongyloides stercoralis Hyperinfection Syndrome: A Neglected Cause of Abdominal Pain

“…Hyperinfection, the syndrome of accelerated autoinfection, is usually the result of an alteration in immune status [ 10 ]. Larvae in non-disseminated hyperinfection are increased in number but confined to the organs normally involved in the pulmonary autoinfective cycle (i.e., GI tract, peritoneum, and lungs), whereas in disseminated infection larvae migrate to organs beyond the range of the pulmonary autoinfective cycle [ 1 ].…”

Streptococcus pyogenes bacteremia and toxic shock syndrome related to Strongyloides stercoralis hyperinfection: a case report

“…It has been related to high-dose as well as low-dose and even to locally administered steroids [4], as well as without any identified immunosuppression [5, 6]. Our patient received multiple intra-articular corticosteroids injections (the last was given 2 months before admission), and an orally administered high-dose prednisone course due to acute hearing loss 7 months prior to admission.…”