Pulmonary squamous cell carcinoma and lymphoepithelial carcinoma – morphology, molecular characteristics and differential diagnosis
Sabina Berezowska,
Marie Maillard,
Mark Keyter
et al.
Abstract:Squamous cell carcinoma (SCC) comprises one of the major groups of non‐small‐cell carcinoma of the lung, and is subtyped into keratinising, non‐keratinising and basaloid SCC. SCC can readily be diagnosed using histomorphology alone in keratinising SCC. Confirmatory immunohistochemical analyses should always be applied in non‐keratinising and basaloid tumours to exclude differential diagnoses, most prominently adenocarcinoma and high‐grade neuroendocrine carcinoma, which may have important therapeutic consequen… Show more
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