Pulmonary Sequestration with Renal Aplasia and Elevated SUV Level in PET/CT

Sen, Sayan; Kuman, Nilgün Kanlıoğlu; Şentürk, Ekrem; Pabuşçu, Engin; Yaman, Ertan

doi:10.1155/2012/276012

Cited by 2 publications

(2 citation statements)

References 8 publications

(17 reference statements)

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“…However, research studies rarely report the false positive 18F-FDG PET observed in pulmonary sequestration and only a few false positive cases using 18F-FDG PET/CT have been reported. [ 9 – 12 ] Median SUV in these patients was 5.83 ± 4.729 which suggested malignancy, and SUVmax in this case is as high as 11.29. Interestingly, 2 of them were extra pulmonary sequestration, and the others were cases of intrapulmonary sequestration combined with pneumonia.…”

Section: Discussionmentioning

confidence: 70%

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Pulmonary sequestration associated with increased serum tumor markers and elevated standard uptake value level in PET/CT

et al. 2018

Medicine

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Rationale:Pulmonary sequestration (PS) is a congenital pulmonary malformation wherein a piece of tissue that ultimately develops into lung tissue is not attached to the pulmonary arterial blood supply, sometimes it is difficult to diagnosis with no specific laboratory tests, discover an abnormal blood supply from aorta by imaging tests is a key step in diagnose.Patient concerns:A 54-year-old male smoker presented with cough, expectoration and blood in the sputum.Diagnoses:Computed tomography (CT) shows lesion in right lung, moderate standard uptake value (SUV) elevation of position-emission tomography/computed tomography (PET/CT) in a part of the lesion, and an increased (1,3)-β-D-glucan assay (G test), Galactomannan enzyme immune-assay (GM test) and tumor marker level, biopsy of lung in different times produced inconclusive results, then finally diagnose of pulmonary sequestration is made by observing an abnormal blood supply from the thoracic aorta and volume change of mass.Interventions:The patient refused lower lobectomy which is the main treatment of PS. He was discharged with oral hemostatic and was advised to undergo regular medical checkups.Outcomes:The patient has been followed for a year under an outpatient regimen. Symptoms of the cough and expectoration were relieved, however, blood in the sputum remains unchanged.Lessons:It suggests the need for criteria for a thorough diagnostic work-up. It put emphasis on the importance of considering PS as part of the diagnosis of a lesion in the lung disease and underscore the blood supply of mass. Bronchoscopy or pulmonary lobectomy and follow up of the patient are important for patients diagnosed with pulmonary sequestration.

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Section: Discussionmentioning

confidence: 70%

“…Importantly, the abnormal blood supply from one or more anomalous systemic arteries to the pathological tissue is helpful for the clinical diagnosis (Table 1 ). [ 9 – 12 ]…”

Section: Introductionmentioning

confidence: 99%

Pulmonary sequestration associated with increased serum tumor markers and elevated standard uptake value level in PET/CT

et al. 2018

Medicine

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Extralobar Pulmonary Sequestration: A Rare Entity

Rai,

Rhakho

et al. 2024

Cureus

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Lung sequestration is a rare congenital anomaly characterized by non-functional lung tissue that lacks normal bronchial communication and receives blood supply from an aberrant systemic artery. Extralobar sequestration (ELS) is less common and usually found in the lower thoracic or upper abdominal regions. It is often diagnosed in infancy or early childhood due to associated congenital anomalies or respiratory symptoms. The complexity of highly variable anatomy and the involvement of multiple systemic arteries pose significant diagnostic and therapeutic challenges. Patients may present with a variety of nonspecific symptoms, such as recurrent respiratory infections, chronic coughs, or unexplained abdominal pain, which often leads to delayed diagnosis. This case report details the unique presentation of extrapulmonary lung sequestration in a 32-year-old male who presented with persistent respiratory symptoms and intermittent abdominal discomfort. Through comprehensive imaging studies and surgical intervention, the diagnosis was confirmed, and the sequestered tissues were successfully resected. This report aims to highlight the importance of considering bilateral extrapulmonary sequestration in differential diagnoses of recurrent respiratory and abdominal symptoms and to discuss the diagnostic approach and management strategies for this rare condition with highly variable anatomy.

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Pulmonary Sequestration with Renal Aplasia and Elevated SUV Level in PET/CT

Cited by 2 publications

References 8 publications

Pulmonary sequestration associated with increased serum tumor markers and elevated standard uptake value level in PET/CT

Pulmonary sequestration associated with increased serum tumor markers and elevated standard uptake value level in PET/CT

Extralobar Pulmonary Sequestration: A Rare Entity

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