Pulmonary Sclerosing Hemangioma Presenting as Solitary Pulmonary Nodule: Dynamic CT Findings and Histopathologic Comparisons

Chung, Myung Jin; Lee, Kyung Soo; Han, Joungho; Sung, Yon Mi; Chong, Semin; Kwon, O Jung

doi:10.2214/ajr.05.0460

Cited by 54 publications

(44 citation statements)

References 16 publications

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“…The alternative designation is sclerosing pneumocytoma since current evidence suggests that sclerosing hemangiomas originate from primitive undifferentiated respiratory epithelial cells (8, 9). Dynamic enhancement characteristics of the tumors depend on the levels of histologic components (papillary, sclerotic, solid, and hemangiomatous); a hemangiomatous or papillary component reveals early and strong enhancement, while a solid or sclerotic component shows slow and persistent enhancement (10). Although these enhancement patterns of sclerosing hemangioma can sometimes look quite similar to that of capillary hemangioma, the former usually do not show a striking peripheral nodular enhancement of the latter on the early arterial phase.…”

Section: Discussionmentioning

confidence: 99%

Recurrent Pulmonary Capillary Hemangioma: Dynamic Contrast-Enhanced CT and Histopathologic Findings

Kim

Han

et al. 2012

Korean J Radiol

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We report the dynamic contrast-enhanced CT and histopathologic findings of a rare case of recurrent pulmonary capillary hemangiomas. The findings consisted of peripheral nodular enhancement at the early arterial phase and a subsequent "central filling-in" enhancement pattern on the delayed scans, which was identical to the well-known enhancement pattern of hemangiomas of the liver. Although there was no evidence of histological malignancy, pulmonary capillary hemangiomas manifested as multiple nodular lesions and showed postoperative recurrence.

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Section: Discussionmentioning

confidence: 99%

Recurrent Pulmonary Capillary Hemangioma: Dynamic Contrast-Enhanced CT and Histopathologic Findings

Kim

Han

et al. 2012

Korean J Radiol

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“…Moreover, although there was no marked difference between the tumor size, density, shape and margin of the PSHs and pulmonary hamartomas, the study showed significantly higher FDG accumulation in the PSHs than in the pulmonary hamartomas. Chung et al (23) suggested that the presence of a hemangiomatous or papillary component in the tumor may lead to increased FDG uptake. Lee et al (21) attempted to analyze the mechanism or histological influencing factors of the increased FDG uptake of PSH.…”

Section: Discussionmentioning

confidence: 99%

18F‑FDG PET/CT characteristics of pulmonary sclerosing hemangioma vs. pulmonary hamartoma

et al. 2018

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Abstract. The radiological features of pulmonary sclerosing hemangioma (PSH) and pulmonary hamartoma are poorly specified. Thus, the present study aimed to compare and analyze the characteristics of fluorodeoxyglucose positron emission tomography/computed tomography ( 18 F-FDG PET/CT) in PSH versus pulmonary hamartoma.18 F-FDG PET/CT characteristic findings of 12 patients with PSH and 14 patients with pulmonary hamartoma were retrospectively reviewed. A total of 12 lesions were detected from the 12 patients with PSH, of which 3 masses exhibited calcification. The mean diameter and standardized maximum uptake value (SUVmax) were 1.9±0.7 cm and 2.6±1.0, respectively, and there was no significant correlation between the lesion size and SUVmax (P>0.05). For the 14 patients with pulmonary hamartoma, 14 lesions were found, of which 4 exhibited calcification. The mean diameter and SUVmax were 1.7±0.8 cm and 1.5±0.6, respectively, and there was a significant correlation between the size and SUVmax (r= 0.625, r 2 = 0.391, P<0.05). Although there was no significant difference between the size of PSH and pulmonary hamartoma (P>0.05), the SUVmax of PSH was significantly higher than that of pulmonary hamartoma (P<0.05). Moreover, the SUVmax of 1.95 was applied as a cutoff for the diagnosis of PSH, and the resulting sensitivity and specificity for PET/CT to differentiate PSH from pulmonary hamartoma were 83.3 and 78.6%, respectively. Although the morphological features were not specific, PSH showed significantly higher FDG accumulation than pulmonary hamartoma on PET/CT imaging, which may aid the differential diagnosis. Further studies with larger populations are warranted to confirm these study results.

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“…CXR characteristics are sharply marked, well defined, solitary, peripheral, homogenous mass without any lobar predilection. [5] On CECT, there is contrast-enhancement of the mass with little or no peripheral calcification. There is absence of infiltration of surrounding tissues along with absence of cavities.…”

Section: Discussionmentioning

confidence: 99%

Diagnosis of sclerosing hemangioma of lung: Don′t rely on fine-needle aspiration cytology diagnosis alone

et al. 2013

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Sclerosing hemangioma is a rare variety of benign pulmonary neoplasm. It usually presents as asymptomatic, solitary, peripheral, circumscribed lesions in middle-aged women. Here, we describe a 46-year-old woman presenting to us for evaluation of right parahilar lung mass. Previous chest radiography done 10 years back showed a lung mass of almost similar size. Computed Tomography (CT)-guided fine-needle aspiration cytology (FNAC) was suggestive of adenocarcinoma of lung. A well-circumscribed, capsulated, ovoid mass measuring 5.6 cm × 4 cm × 3 cm, adjacent to the transverse fissure of the right lung was excised by lateral thoracotomy. Histopathological examination along with immunohistochemistry was suggestive of sclerosing hemangioma of lung. A pathologist must consider the clinicoradiological features before coming to a final diagnosis of lung malignancy from FNAC. Whenever there is any confusion regarding lung mass, thoracotomy must be done for arriving at an exact diagnosis from histopathology.

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Pulmonary Sclerosing Hemangioma Presenting as Solitary Pulmonary Nodule: Dynamic CT Findings and Histopathologic Comparisons

Abstract: On dynamic CT, sclerosing hemangioma has strong and rapid enhancement attributed histopathologically to the presence of hemangiomatous or papillary components in the tumor.

Cited by 54 publications

References 16 publications

Recurrent Pulmonary Capillary Hemangioma: Dynamic Contrast-Enhanced CT and Histopathologic Findings

Recurrent Pulmonary Capillary Hemangioma: Dynamic Contrast-Enhanced CT and Histopathologic Findings

18F‑FDG PET/CT characteristics of pulmonary sclerosing hemangioma vs. pulmonary hamartoma

Diagnosis of sclerosing hemangioma of lung: Don′t rely on fine-needle aspiration cytology diagnosis alone

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