Pulmonary Rehabilitation in the Era of Multimorbidity and Multiple Disabilities (MMD)

Kohzuki, Masahiro; Cho, Chaeyoon; Lee, Chaewon; Harada, Taku

doi:10.17140/prrmoj-se-2-103

Cited by 1 publication

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References 6 publications

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“…As super-aged society has come, the number of persons with multimorbidity and multiple disabilities (MMD) (Kohzuki, 2014) and their needs of rehabilitation have increased rapidly more than expected (Kohzuki, 2014). Exercise testing offers the investigator the unique opportunity to study simultaneously the cellular, cardiovascular, and ventilatory systems' responses under conditions of precisely controlled metabolic stress.…”

Section: ⅴ Exercise Testingmentioning

confidence: 99%

Importance of Physical Activity and VO2max:

Kohzuki

Cho

Takahashi

et al. 2018

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Cardiorespiratory fitness (CRF) is defined as the ability of the circulatory and respiratory systems to supply oxygen during sustained physical activity and is usually expressed as maximal oxygen uptake (V ． O2max) during maximal exercise testing. There are five major determinants of V ． O2max: functions of the heart, lung, kidney, muscle, and blood (hemoglobin). Cardiac output, pulmonary diffusion capacity, oxygen-carrying capacity, renal function, and other peripheral limitations like muscle diffusion capacity, mitochondrial enzymes, and capillary density are all examples of V ． O2max determinants. V ． O2max, measured by cardiopulmonary exercise testing, provides what is probably the most sensitive assessment of the effect of new therapy on the function of any diseased organ system whose major function is to couple pulmonary gas exchange to cellular respiration. For example, it is important to determine whether new medical, surgical, and rehabilitative procedures can effectively intervene to improve the gas transport capability of a diseased organ system.

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Section: ⅴ Exercise Testingmentioning

confidence: 99%