Pulmonary nuclear medicine

Miller, R F; O’Doherty, Michael

doi:10.1007/bf00177058

Cited by 29 publications

(14 citation statements)

References 89 publications

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“…This is similar to the result of previous reports [21,22]. On the other hand, this study also showed significant prolongation of Tc-99m DTPA radioaerosol lung clearance in AIPT-II subjects.…”

Section: Discussionsupporting

confidence: 94%

Value of technetium-99m diethyltriamine pentaaceticacid radioaerosol inhalation lung scintigraphy for the stage of amiodarone-induced pulmonary toxicity

Durmuş-Altun¹,

Altun²,

Salihoğlu³

et al. 2004

International Journal of Cardiology

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Section: Discussionsupporting

confidence: 94%

Value of technetium-99m diethyltriamine pentaaceticacid radioaerosol inhalation lung scintigraphy for the stage of amiodarone-induced pulmonary toxicity

Durmuş-Altun¹,

Altun²,

Salihoğlu³

et al. 2004

International Journal of Cardiology

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“…The currently available techniques for lung scintigraphy have recently been reviewed [12]. Perfusion scintigraphy is most commonly performed using technetium-99m-labelled albumin macroggregates.…”

Section: Perfusion and Ventilation Imagingmentioning

confidence: 99%

The value of lung scintigraphy in the diagnosis of pulmonary embolism

et al. 1993

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The role of lung scintigraphy in the diagnostic management of patients with clinically suspected pulmonary embolism is reviewed. Evidence is provided that a normal perfusion scan excludes clinically relevant pulmonary embolism, and that a high probability lung scan, defined as a segmental perfusion defect with locally normal ventilation, sufficiently confirms the presence of pulmonary embolism in the majority of these patients. Furthermore, this review assesses the possibility of non-invasive tests for the diagnosis or exclusion of venous thromboembolic disease as a means of avoiding pulmonary angiography in patients with lung scan outcomes that are neither normal nor high probability.

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“…On the other hand, treatment with anticoagulants will result in bleeding complications, which are fatal and major in 1% and 7% per treatment year, respectively (5,6 (12). These particles are injected intravenously with the patient supine and taking a deep breath, which guarantees optimal dispersion into the pulmonary vascular bed, where they become trapped.…”

mentioning

confidence: 99%

Lung Scintigraphy and Helical Computed Tomography for the Diagnosis of Pulmonary Embolism: A Meta-Analysis

Beek

Brouwers

Song

et al. 2001

Clin Appl Thromb Hemost

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To assess the diagnostic value of lung scintigraphy and helical computed tomography (hCT) in patients with suspected pulmonary embolism (PE), all English-language articles that described lung scintigraphy and hCT in patients with suspected PE were retrieved. Articles were assessed for strength of methodology, based on nine a priori-defined criteria. Parameters of diagnostic accuracy and results of management studies were calculated and evaluated. Lung scintigraphy is diagnostic in approximately 50% of patients with suspected PE. A normal perfusion scan has a chance of recurrent PE in two of 693 patients (0.3%; 95% CI: 0.2-0.4%; fatal in 0.15%). A high-probability lung scan is corrected with angiographically proven PE in 308 of 350 patients (88%; 95% CI: 84-91%). Pulmonary embolism was proven in 385 of 1529 patients (25%; 95% CI: 24-28%) with a nondiagnostic lung scan. Helical CT studies were compared with angiography and lung scintigraphy in 1171 patients, with a prevalence of PE of 39%. The sensitivity and specificity of hCT was 283/320 (88%; 95% CI: 83-91%) and 374/408 (92%; 95% CI:89-94%), respectively. Only one prospective management study using hCT was available. In patients in whom anticoagulants were withheld based on a normal hCT study, recurrent thromboembolic events occurred in six of 109 patients (5.5%; 95% CI: 2-12%), with one fatality (1%; 95% CI: 0.02-4.3%). Lung scintigraphy is evaluated extensively and yields a diagnostic result in 50% of patients. Helical CT has similar positive predictive value to a high-probability lung scan. However, the exact role of hCT in the management of patients with suspected PE needs to be determiined in prospective studies.

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Pulmonary nuclear medicine

Cited by 29 publications

References 89 publications

Value of technetium-99m diethyltriamine pentaaceticacid radioaerosol inhalation lung scintigraphy for the stage of amiodarone-induced pulmonary toxicity

Value of technetium-99m diethyltriamine pentaaceticacid radioaerosol inhalation lung scintigraphy for the stage of amiodarone-induced pulmonary toxicity

The value of lung scintigraphy in the diagnosis of pulmonary embolism

Lung Scintigraphy and Helical Computed Tomography for the Diagnosis of Pulmonary Embolism: A Meta-Analysis

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