Pulmonary nodules with a cavity and intracranial mass: Rare manifestations of childhood sarcoidosis

Primary cavitary sarcoidosis: A case report, systematic review, and proposal of new diagnostic criteria

“…A systematic review of the PubMed database using the free text terms: Sarcoidosis AND cavit* yielded 311 references of which 17 citations [25 cases, Table 1 ] were that of PCS. [ 6 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 ] The cases have been reported from across the globe including areas with high tuberculosis prevalence,[ 23 24 ] further exemplified by the index case. The patients with PCS are usually young (mean age, 32.4 [range, 12-63] years), show no gender predilection (M:F; 14:11) and can be asymptomatic.…”

Pituitary Sarcoidosis in a Pediatric Patient Successfully Treated With Adalimumab and Methotrexate

“… 5 We identified 13 additional cases (counting ours) not listed in that review. 6 - 17 Symptoms tend to differ based on the age of presentation; seizures are more common in younger children, whereas cranial nerve palsies predominate in older children and adolescents. 2 Hypothalamic/pituitary dysfunction, headaches, meningismus, central nervous system mass lesions, and peripheral neuropathies are other manifestations that can occur across all ages.…”

Neurologic Manifestations of Lung Disease

“…A number of conditions may give rise to the pulmonary-nervous system syndrome, whereby the neurologic manifestations will depend on the site of involvement in the nervous system. Some of these conditions are: Infections [62][63][64][65][66] (mycoplasma, legionella, tuberculosis, aspergillosis, cryptococcosis); toxins (organophosphates); 67 sarcoidosis, [68][69][70][71] collagen vascular diseases; [72][73][74] and miscellaneous (such as Wegener's granulomatosis, [75][76][77] necrotizing sarcoid granuloma, 78 and histiocytosis 79 ).…”