Pulmonary Mucosa-Associated Lymphoid Tissue Lymphoma: Two Cases Report

Abstract

Primary pulmonary lymphoma (PCL) is rare and represents only 0.5-1% of the malignant lung tumour. Pulmonary MALT lymphoma is the most common histological aspect. The pathophysiological mechanism remains poorly known, unlike other locations of MALT lymphoma, no pathogen has so far been associated with the lung localization of the disease. It is characterized by slow evolution and atypical clinical presentation which delays diagnosis. The form «pneumonic» on the imaging allows to evoke the diagnosis while the confirmation is based on the immunohistochemical study which detects the presence of positive CD20 cell. Therapeutic options include surveillance of indolent types of LPP, surgery in localized tumors, chemotherapy in diffuse forms. We report two observations of diagnosed pulmonary MALT lymphoma on a scanno-guided bronchial and pulmonary biopsy.