Pulmonary lymphangitic carcinomatosis from hypopharyngeal adenosquamous carcinoma

Abstract

Although pulmonary lymphangitic carcinomatosis (PLC) is not uncommon for breast, bronchial, and stomach cancers, it is rarely associated with head and neck malignancy. A case of PLC is reported with the primary lesion being an adenosquamous carcinoma of the hypopharynx. A literature review is discussed, highlighting the varied radiographic picture of PLC, the possible diagnostic modalities, the proposed pathogenesis, and the treatment options. The prognosis even if antemortum diagnosis and treatment are given remains fatal, although with temporary improved quality of life and lengthened survival. There is hope that with greater awareness of the disease process an increased incidence of diagnosis may allow progress to be made in therapeutic interventions.

Systemic lymphangitic carcinomatosis from unknown primary cancer mimicking lung disease in a new coronavirus infection (COVID-19): a case report

“…Реже первичная опухоль локализуется в почках (7,9 %), предстательной железе (5,8 %) или мочевом пузыре (2,2 %) [1]. В единичных случаях отмечалось первичное поражение пищевода, поджелудочной железы, желчного пузыря, мочеточников, прямой, ободочной кишки, губы, нижней челюсти, глотки, миндалин, гортани, щитовидной железы [1,[4][5][6][7][8][9]. В доступной литературе мы не нашли описания морфологически и иммуногистохимически подтвержденных случаев канцероматозного лимфангита при невыявленной первичной локализации опухоли с системным поражением внутренних органов.…”

A rare presentation of Pulmonary Lymphangitic Carcinomatosis in cancer of lip: case report

“…Head and neck cancers very rarely have lung metastasis in the form of PLC. Oropharyngeal and hypopharyngeal cancers have been reported to have such type of metastasis [1]. Cancer of lip is a common malignancy in Indian subcontinent mainly due to tobacco chewing and that these cancers are detected in early stages due to its visible location, a spread to lung is rare and they are of typical nodular metastases.…”

Pulmonary Lymphangitic Sarcomatosis from Cutaneous Angiosarcoma: an Unusual Presentation of Diffuse Interstitial Lung Disease

“…The incidence of pulmonary lymphangitic carcinomatosis (PLC) accounts for only 6% of pulmonary metastases (1). Primary carcinomas such as breast, lung and stomach are the most common primary tumors reported to produce this form of dissemination (2).…”