Pulmonary lobectomy for lung cancer: a prospective study to compare patients with forced expiratory volume in 1 s more or less than 80% of predicted

Santambrogio, Luigi; Nosotti, Mario; Baisi, Alessandro; Ronzoni, G; Bellaviti, Nadia; Rosso, Lorenzo

doi:10.1016/s1010-7940(01)00886-7

Cited by 54 publications

(34 citation statements)

References 14 publications

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“…In patients with lung disease, careful evaluation of the type, degree and location of the lung abnormalities is important in order to select the best lung resection. This is particularly relevant in patients with emphysema of the upper lobes in whom a lobectomy will have a lung volume reduction effect, with improvement of postoperative lung function, whereas a segmentectomy would not achieve the same results [47]. Conversely, the preservation of lung function in patients with small lung cancers and anticipated long survival is important, considering the possibility of further lung resections to treat second primary lung tumours.…”

Section: Post-operative Pulmonary Functionmentioning

confidence: 99%

Sublobar resection for lung cancer

Rami–Porta

Tsuboi²

2008

European Respiratory Journal

101

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Sublobar resection for small lung cancers has been debated frequently and is still a controversial issue. The only randomised trial comparing lobectomy with sublobar resections found a significantly higher recurrence rate for the latter, but failed to show significant differences in survival, although survival was better for the lobectomy group. One meta-analysis and several nonrandomised comparisons have confirmed these results. In general, lobectomy and sublobar resections have similar 5-yr survival rates. Local recurrence after wedge resection is higher than after segmentectomy. However, for patients aged .71 yrs, lobectomy and wedge resection are associated with similar survival. For tumours of f2 cm, segmentectomy is equivalent to lobectomy, but survival after segmentectomy is worse if performed for larger tumours. For both segmentectomy and wedge resection, tumour margins should be o1 cm wide to avoid recurrence. For pure bronchioloalveolar carcinoma of f2 cm, diagnosed intraoperatively with certainty, sublobar resection seems equivalent to lobectomy, and because there is no nodal involvement, systematic nodal dissection may not be necessary. In case of doubt, however, lobectomy with systematic nodal dissection will ensure complete resection and adequate staging. More randomised trials are needed to confirm all these issues.

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Section: Post-operative Pulmonary Functionmentioning

confidence: 99%

Sublobar resection for lung cancer

Rami–Porta

Tsuboi²

2008

European Respiratory Journal

101

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“…Many studies have shown the minimal loss or even the improvement in pulmonary function after lobectomy in COPD patients with cancer, questioning the traditional operability criteria mostly based on pulmonary parameters (26)(27)(28)(29)(30)(31)(32)(33).…”

Section: Pulmonary Function Evaluationmentioning

confidence: 99%

Preoperative functional workup for patients with advanced lung cancer

Brunelli

2016

J. Thorac. Dis.

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Locally advanced lung cancer remains a surgical indication in selected patients. This condition often demands larger resections. As a consequence preoperative functional workup is of paramount importance to stratify the risk and choose the most appropriate treatment. We reviewed the current evidence on functional evaluation with a special focus on specific aspects related to locally advanced lung cancer stages (i.e., risk after neoadjuvant treatment, pneumonectomy). Evidence is discussed to provide information that could assist clinicians in their preoperative workup of these challenging patients.

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“…A growing number of studies in the recent years have reported an improvement of respiratory function after lobectomy in some patients affected by COPD [29], or at least a minimal impairment of respiratory function indicated by better apoFEV% (actual postoperative) than ppoFEV1% (predicted postoperative) [30]. In such cases Authors have hypothesized that lobectomy could have a lung volume reduction surgery (LVRS) effect [31].…”

Section: Lung Volume Reduction Era and Its Importance In Lung Cancer mentioning

confidence: 99%