Pulmonary Inflammatory Myofibroblastic Tumor Resected by Video-Assisted Thoracoscopic Surgery: Report of a Case

Nakamura, Hiroki; Kawasaki, Norihito; Taguchi, Masahiko; Kitamura, Hajime

doi:10.1007/s00595-006-3344-0

Cited by 8 publications

(5 citation statements)

References 26 publications

(20 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although classic PIMT is defined as a slow-growing, solitary, round to oval-shaped and well-circumscribed mass in the peripheral regions of the lower lobes (16), CT manifestations of PIMT are generally diverse. A number of studies have reported that PIMTs present as ill-defined or irregular lesions (6,16,22–24). In addition, other CT findings, including calcification, cavity, necrosis, obstructive atelectasis and pneumonia have also been reported in several previous studies (8,9,15,16,18,20).…”

Section: Discussionmentioning

confidence: 99%

Imaging observations of pulmonary inflammatory myofibroblastic tumors in patients over 40 years old

Zhu

et al. 2015

Oncology Letters

View full text Add to dashboard Cite

Pulmonary inflammatory myofibroblastic tumors (PIMTs) are extremely rare in adults. If occurring in patients >40 years old, PIMT should be rapidly distinguished from lung cancer. The present study aimed to characterize the imaging features of PIMT in patients >40 years old in order to improve the diagnosis of PIMT. The imaging data of 10 patients with PIMT were reviewed retrospectively. Of the patients, eight underwent computed tomography (CT), two underwent positron emission tomography (PET)/CT and four underwent single-photon emission computed tomography (SPECT). Unenhanced CT revealed 10 lesions with a maximum diameter ranging between 5 and 57 mm located in the lower (n=6) or upper (n=4) lobe, in a peripheral (n=9) or central (n=1) region, and that were well- (n=4) or ill-defined (n=6), and round to oval (n=5) or irregular (n=5) in shape. Calcification (n=3), necrosis (n=6), cavity (n=4), air bronchogram (n=6) and obstructive pneumonia (n=1) were also observed in the patients. Contrast-enhanced CT revealed six lesions with moderate to high contrast enhancement in the arterial and venous phases, including four lesions with delayed enhancement. PET/CT identified two lesions with increased tracer uptake that were homogeneous and heterogeneous and each exhibited a maximal standard uptake value (SUVmax) of 6.0 and 5.4, respectively. The delayed PET/CT revealed foci that each exhibited an increased SUVmax of 6.9 and 5.9, respectively. SPECT demonstrated no definitive bone metastases, but did reveal atypical hypertrophic pulmonary osteoarthropathy in one patient. The combined imaging methods may lead to a more precise evaluation of PIMT in patients >40 years old.

show abstract

Section: Discussionmentioning

confidence: 99%

Imaging observations of pulmonary inflammatory myofibroblastic tumors in patients over 40 years old

Zhu

et al. 2015

Oncology Letters

View full text Add to dashboard Cite

show abstract

“…11 cases, including our two cases ( Table 1). [3][4][5][6][7][8][9][10] As shown in Table 1, the mean age of the patients was 49 ± 13 years, with an age range of 26 to 65 years; four patients were male and seven were female. The mean maximum tumor size was 2.0 ± 0.8 cm, with a range of 0.8 to 3.5 cm.…”

Section: Discussionmentioning

confidence: 99%

Inflammatory Pseudotumor Suspected of Lung Cancer Treated by Thoracoscopic Resection

Hirai

Katayama

Chatani

et al. 2011

ATCS

View full text Add to dashboard Cite

We report a relatively rare surgical treatment for two cases of inflammatory pseudotumors of the lung. In case 1, a 52-year-old male with a history of left chest pain was admitted to our hospital for an abnormal nodule with an irregular margin that was detected in the left upper lung field. The nodule, measuring 15 mm in diameter, was larger than the one observed six months earlier, which had been removed by a thoracoscopic resection. In case 2, a 64-yearold female with a history of chronic cough and hemoptysis was admitted to our hospital, and an abnormal nodule with pleural indentation was detected in the lower left lung field. The nodule, measuring 8 mm in diameter, was also removed by a thoracoscopic resection. In both cases, the histologic examination enabled us to diagnose the lesion as an inflammatory pseudotumor. In general, it is very difficult to differentiate inflammatory pseudotumors from malignant tumors of the lung. The best treatment for inflammatory pseudotumors is usually early and complete surgical resection, since it can lead to improved survival. Therefore, we consider thoracoscopy-aided surgery to be less invasive and more useful than other surgical methods in the diagnosis and treatment of inflammatory pseudotumor of the lung.

show abstract

“…Inflammatory myofibroblastic tumor (IMT) is a well‐described disease and can occur in various organs and tissues such as the lung, skin, soft tissues, breast, gastrointestinal tract, pancreas, oral cavity, bone, and central nervous system 1–4 . Various synonyms like inflammatory pseudotumor, plasma cell granuloma, pseudosarcomatous myofibroblastic proliferation, plasma cell pseudotumor, inflammatory myofibrohistiocytic proliferation, atypical myofibroblastic tumor and post operative spindle nodule, are interchangeably used to describe this unusual pathological entity 5 .…”

Section: Introductionmentioning

confidence: 99%

Primary inflammatory myofibroblastic tumor of the diaphragm: Report of a case

Zhang

et al. 2013

Thoracic Cancer

View full text Add to dashboard Cite

We report a case of primary inflammatory myofibroblastic tumor of the diaphragm in a 64-year-old man. The patient was hospitalized for a computed tomography (CT)-detected large tissue mass at the left lower lung field. Complete tumor excision followed by pathological investigation was performed. Microscopically, the tumor showed staggered arrangements of spindle myoepithelial cells, lymphoblastic and eosinophil cells. Immunohistochemically, the proliferating spindle cells showed positive staining for smooth muscle actin, vimentin, CD68 and Desmin, but negative for cytokeratin, leukocyte common antigen, epithelial membrane antigen, and S-100. This is the first reported inflammatory myofibroblastic tumor of the diaphragm found in an adult. The postoperative course was uneventful and the patient had no recurrence 18 months after surgery.

show abstract

Pulmonary Inflammatory Myofibroblastic Tumor Resected by Video-Assisted Thoracoscopic Surgery: Report of a Case

Cited by 8 publications

References 26 publications

Imaging observations of pulmonary inflammatory myofibroblastic tumors in patients over 40 years old

Imaging observations of pulmonary inflammatory myofibroblastic tumors in patients over 40 years old

Inflammatory Pseudotumor Suspected of Lung Cancer Treated by Thoracoscopic Resection

Primary inflammatory myofibroblastic tumor of the diaphragm: Report of a case

Contact Info

Product

Resources

About