Pulmonary Hypertension: Diagnosis and Management

Torbicki, Adam

doi:10.3390/diagnostics11061066

Cited by 1 publication

(1 citation statement)

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“…Combined with systemic vasoconstriction and neurohumoral activation, these compensatory mechanisms increase PAP to improve blood flow through the obstructed pulmonary vascular bed to stabilize systemic blood pressure. [3,[6][7][8] According to this mechanism, the RV will then undergo morphological changes to compensate for pressure overload.…”

Section: Clinical Perspectivementioning

confidence: 99%

Value of Coronary Sinus During Computed Tomography Pulmonary Angiography for Predicting Pulmonary Hypertension in Patients with Acute Pulmonary Embolism

Zhang¹,

Qian²,

et al. 2023

Cardiology Discovery

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Objective: Computed tomography pulmonary angiography (CTPA) parameters are valuable for predicting pulmonary hypertension (PH) in patients with pulmonary embolism (PE). However, few studies have used the coronary sinus ostium area (CSOA), derived from CTPA, to detect PH. This study aimed to compare the prognostic values of the CSOA, coronary sinus ostium diameter (CSOD), and right ventricular (RV)/left ventricular (LV) ratio for PH. Methods: This study retrospectively analyzed 78 patients (mean age, (51.94 ± 12.33) years; 53.8% male) with acute PE confirmed by CTPA at the Sixth and Eighth Medical Centers of the People’s Liberation Army General Hospital between June 2018 and June 2020. Patients were categorized into 2 groups using a pulmonary artery systolic pressure (PASP) cut-off of 30 mmHg. CTPA parameters were compared between these groups. Results: Patients with PASP >30 mmHg (n = 22) had a larger CSOA, CSOD, RV diameter, RV/LV ratio, and inferior vena cava diameter compared with patients with PASP ≤30 mmHg (n = 56). The CSOA had an area under the receiver-operating characteristic curve (AUC, 0.84; 95% confidence interval (CI), 0.74–0.94; P < 0.001) similar to that of the RV/LV ratio (AUC, 0.85; 95%CI, 0.73–0.99; P < 0.001), while that of the CSOD was smaller (AUC, 0.66; 95%CI, 0.51–0.81; P < 0.05). Conclusion: Both CSOA and CSOD demonstrated a good ability to predict PH, while CSOA better predicted PASP >30 mmHg.

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Section: Clinical Perspectivementioning

confidence: 99%