Pulmonary hemosiderosis

Levy, J.B.; Wilmott, Robert W.

doi:10.1002/ppul.1950020612

Cited by 12 publications

(2 citation statements)

References 51 publications

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“…23 However this diagnosis has faced scrutiny as these results have not been reproduced in other trials. 24 Only one patient in this study (in the IPH group) had milk precipitins obtained, and the result was negative. However, it is still the authors' policy to remove cow's milk from the diet of infants with suspected IPH.…”

Section: Discussionmentioning

confidence: 86%

Pulmonary capillaritis in children: A review of eight cases with comparison to other alveolar hemorrhage syndromes

Fullmer

Langston

Dishop

et al. 2005

The Journal of Pediatrics

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Section: Discussionmentioning

confidence: 86%

Pulmonary capillaritis in children: A review of eight cases with comparison to other alveolar hemorrhage syndromes

Fullmer

Langston

Dishop

et al. 2005

The Journal of Pediatrics

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“…Other causes of PH, such as cardiac structural disorders giving increased pulmonary venous pressure, have also been excluded. In contrast to adult PH, the majority of PH in infants and children is idiopathic (9). A retrospective study of 30 childhood cases over 20 years in Greece (10) speculated the possible role of pesticides; other toxicants have been implicated in older patients (11 (19) is one of several environmental fungi that produce very potent compounds toxic to humans and animals.…”

Section: Introductionmentioning

confidence: 99%

Overview of investigations into pulmonary hemorrhage among infants in Cleveland, Ohio.

Dearborn

Yike

Sorenson

et al. 1999

Environ Health Perspect

164

106

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Idiopathic pulmonary hemorrhage was diagnosed in 37 infants in the Cleveland, Ohio, area between 1993 and 1998. This rare disorder has been related to 12 deaths, including 7 originally thought to be sudden infant death syndrome. Thirty of the infants were African American, all of whom lived in a limited geographic area of eastern metropolitan Cleveland, an area of older housing stock. An investigation led by the Centers for Disease Control and Prevention has found an association with household exposure to a toxigenic mold, Stachybotrys chartarum, and other fungi. The rapidly growing lungs of young infants appear to be especially vulnerable to the toxins made by toxigenic molds. Environmental tobacco smoke was frequently present in the infants' homes and may be a trigger precipitating the acute bleeding. Stachybotrys, although not thought to be a common mold, is known to have a wide geographic distribution. An additional 101 cases of acute, idiopathic pulmonary hemorrhage have been reported in infants in the United States over the past 5 years. In this overview, the investigations are summarized, the clinical profile is described, the toxicity of S. chartarum is discussed, and pathophysiologic concepts are presented.

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