Pulmonary Gumma

Secondary Pulmonary Syphilis: Report of A Likely Case and Literature Review

“…Even epithelioid cell granulomas occur occasionally in secondary syphilis, especially in the late stage [7]. In our case, the radiological presentation-multiple, subpleural, excavated, well-defined nodules-was very similar to previous descriptions of pulmonary gumma [18], but histological examination did not confirm this impression. However, the biopsy specimen was small, and the biopsy was performed on a nodule that was not excavated.…”

Sífilis secundária com acometimento pulmonar

“…8,9 A sífilis secundária adquirida raramente acomete os pulmões. [8][9][10][11] Na revisão bibliográfica feita, foram encontrados oito casos de acometimento pulmonar na sífilis secundária, sendo quatro deles com nódulo pulmonar solitário, dois com nódulos pulmonares múltiplos e dois com lesões infiltrativas, sendo um com padrão retículo-nodular. Todos esses casos relatados preenchiam os critérios de Colleman et al 9 O caso aqui relatado é possivelmente o terceiro da literatura que apresenta nódulos pulmonares múltiplos.…”

Secondary syphilis with pulmonary involvement: Report of a case with emphasis to the high-resolution CT and magnetic resonance findings

“…The largest nodule was pleural based and showed central necrosis, characterized by lower attenuation area on CT and hyperintensity on T2 weight images on MR. Post contrast images showed homogeneous enhancement in all nodules, except in the central area of the largest lesion. Concerning the imaging findings in patients with tertiary syphilis, bilateral hilar lymph node enlargement, interstitial disease with evolution to diffuse pulmonary fibrosis if not treated, bronchiectasis, miliary nodules and masses are most frequently reported 4,11 . Jankovic et al 11 describe a radiological pattern similar to sarcoidosis and other diseases (coal worker's disease, silicosis, idiopathic pulmonary fibrosis and hypersensivity pneumonitis).…”

“…However, the re-emergence of the venereal disease associated with the human immunodeficiency virus (HIV) infection may be responsible by the increase of the incidence of this infection 1 . Only a few authors have described the imaging features in patients with secondary pulmonary syphilis [3][4][5][6][7][8][9] . The most common demonstrated high-resolution CT in these cases includes solitary pulmonary nodules, mainly in the middle and lower lungs zones, multiple pulmonary nodules and reticulonodular pattern 3,5,6,9 .…”