Pulmonary function in mitral valve disease

Respiration

“…Ventilation has been evaluated in a variety of pulmonary diseases. Vital capacity was also reduced in various forms of heart failure (119) and in mitral stenosis, sometimes by 75 per cent, the reduction being correlated with degree of cardiac decompensation (88) or with pulmonary artery pres sure (103). Pathological studies of hyaline membranes implicated an obstructive element (67).…”

“…However, dur ing perfusion of the right atrium with well oxygenated blood, there was a much smaller rise in pulmonary artery pressure, suggesting mediation of the response by receptors for hypoxia located in capillaries as well as air passages. Some type of active vasoconstriction was also postulated in the pulmonary hy pertension sometimes seen in mitral stenosis (88). Whether pulmonary vascular resistance increased was not clear.…”

Pulmonary Function and Arterial Stiffness in Chronic Heart Failure

“…For instance, a study assessing 20 stable ambulatory individuals presenting congestive heart failure caused by cardiomyopathy indicated that tidal expiratory flow limitation is common [7]. In addition, patients with stable mitral valve disease display reduced forced expiratory volume in 1 s (FEV 1 ) and forced vital capacity (FVC), and increased residual volume (RV), which were associated with valvular disease severity [8]. The cardiothoracic ratio was shown to be inversely correlated with total lung capacity as well as with vital capacity [9].…”