Pulmonary Function in Idiopathic Scoliosis

Gazioglu, Kuddusi; Goldstein, Louis A.; Femi-Pearse, D; Yu, Paul N.

doi:10.2106/00004623-196850070-00008

Cited by 48 publications

(10 citation statements)

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“…Primiano et al [27] observed elevated pulmonary artery pressure, right ventricular dysfunction, and even cor pulmonale in patients with severe idiopathic scoliosis. An inverse correlation exists between the degree of spinal curvature and pulmonary function [15,29,33]. Therefore, spinal fusion has been recommended for patients with compromised cardiovascular or pulmonary status associated with progressive spinal deformities [13,33].…”

Section: Discussionmentioning

confidence: 99%

“…All patients with scoliosis were allowed to walk on the third or fourth postoperative day. The mean stay in hospital was 18 (12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22) days. The patient with severe thoracic kyphosis wore an extension brace (TLSO) for 3 months postoperatively.…”

Section: Methodsmentioning

confidence: 99%

“…The operations and all posttransplant surgical treatments were performed at the Hospital for Children and Adolescents, University of Helsinki, Helsinki, Finland. Retrospective review of the patient records revealed that six children with a mean age of 14.8 (12)(13)(14)(15)(16)(17) years had undergone surgical correction of spinal deformity ( Table 1). None of the six children had been treated conservatively with a brace prior to surgical treatment.…”

Section: Patients and Medicationmentioning

confidence: 99%

“…All 211 cases of heart, liver, and kidney transplantations performed in children in our country were reviewed. Six patients had undergone surgical correction of spinal deformity at a mean age 14.6 (range [12][13][14][15][16][17] years. Clinical data of the patients were evaluated.…”

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confidence: 99%

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Surgical correction of spinal deformities after solid organ transplantation in childhood

et al. 2006

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A review of the current literature reveals no systematic analyses of the results of surgical correction of spinal deformity after pediatric organ transplantation. We therefore evaluated clinical and radiographic outcomes of spinal deformity correction after solid organ transplantation in childhood and adolescence. All 211 cases of heart, liver, and kidney transplantations performed in children in our country were reviewed. Six patients had undergone surgical correction of spinal deformity at a mean age 14.6 (range 12-17) years. Clinical data of the patients were evaluated. Radiographs of the whole spine were taken preoperatively, immediately after, at 2-year, and final follow-up visits. The Scoliosis Research Society (SRS) questionnaire was completed and a physical examination was performed at the final follow-up visit. The mean follow-up after spinal surgery was 4.9 years (range 2-7.6 years). Four patients developed scoliosis after organ transplantation without any evidence of scoliosis prior to organ transplantation. One patient with congenital scoliosis was operated on after kidney transplantation. One boy had osteoporosis and severe local kyphosis due to vertebral compression fractures. Four patients underwent anterior and posterior surgery, two posterior only. The mean preoperative Cobb angle of the thoracic curve was 54°(range 42-69°) in the patients with scoliosis. The postoperative values were 30°(26-38°) immediately after instrumentation and 39°(34-42°) at the final followup visit. The patient with vertebral compression fractures and progressive kyphosis had 70°curve before surgery, 23°immediately after the operation, and 60°at the final check up. The mean total score on the SRS questionnaire was 95.5 (range 90-101). There is a relatively high incidence (2.8%) of spinal deformities needing operative treatment after solid organ transplantation. Possible etiologies for spinal deformities are growth disturbance and muscle weakness due to the basic disease. The other important factors are related to immunosupressive medication, especially glucocorticoids needed after transplantation. Primary correction of these deformities was satisfactory, but during followup, a certain amount of recurrence of the curves was evident. Poor bone quality may explain some of the loss of correction.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Patients and Medicationmentioning

confidence: 99%

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confidence: 99%

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Surgical correction of spinal deformities after solid organ transplantation in childhood

et al. 2006

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“…Thus Gazioglu et al (1968) found a 17% improvement in spirometric values 1 year after spinal fusion, and Lindh & Bjure (1975) noted an improvement of 10% at 18 months. Zorab et al (1979) found little measurable increase in lung volumes after corrective spinal surgery, and Westgate & Moe (1969) reported a decrease of 6% of vital capacity during the first and second years after instrumentation for kyphoscoliosis.…”

Section: Respiratory Functionmentioning

confidence: 94%