Pulmonary function and health-related quality of life in patients with early onset scoliosis after repeated traditional growing rod procedures

Abstract

Purpose The purpose of this study was to investigate pulmonary function and health-related quality of life after traditional growing rod (TGR) procedures. Methods Between January 2006 and December 2017, a retrospective observational study of 17 early onset scoliosis (EOS) patients with a mean follow-up of 6.2 years (2.3 to 10.4) was conducted. The forced expiratory volume in one second (FEV1), expiratory forced vital capacity (FVC) and 24-Item Early Onset Scoliosis Questionnaire (EOSQ-24) score before the index surgery and at last follow-up were investigated. Results The mean percentage of predicted FEV1 improved from 50% (20% to 86%) to 53% (15% to 80%; p = 0.08); and the mean percentage of predicted FVC improved from 51% (24% to 81%) to 55% (25% to 89%; p = 0.06). The mean EOSQ-24 score was 78.2 (58 to 90) preoperatively and 77.2 (55 to 88) at last follow-up, there was no statistical difference (p = 0.70). The subdomain scores of pulmonary function (p < 0.01) and daily living (p < 0.01) significantly improved, whereas the subdomain scores of pain (p < 0.01), emotion (p < 0.01) and satisfaction (p = 0.02) significantly declined at last follow-up. Conclusion The TGR procedure was associated with stable pulmonary function and decline in EOSQ-24 pain, emotion and satisfaction scores. Level of Evidence Level III, retrospective cohort study.

The application of finite element analysis to determine the optimal UIV of growing-rod treatment in early-onset scoliosis

“…EOS is a spinal deformity with the characteristic of early occurance, rapid progression, and continuous growth of the spine, with a significant risk of cardiopulmonary insufficiency (Chang et al, 2021;Zhang et al, 2022). Patients with severe spinal curvature usually require spinal correction with growing rods after the failed attempts at conservative treatment (Akbarnia et al, 2022;Heffernan et al, 2022).…”

Early Onset Scoliosis and Adolescent Idiopathic Scoliosis: A Review of the Literature and Correlations With Pulmonary Dysfunction

“…In a retrospective observational study conducted by Chang et al, they found that there was no statistically significant increase in forced expiratory volume in one second (FEV1) and forced vital capacity (FVC) (an increase by 3% and 4% in both parameters, respectively) after repeated traditional growing rod procedures. In addition, almost 30% of patients exhibited a decline in the percentage of predicted FEV1 and FVC at the last follow-up [ 39 ]. PFTs also serve as useful practical parameters in evaluating post-treatment management of patients.…”

“…Even in cases where pulmonary function and daily living significantly improved after surgical intervention, other important aspects regarding QOL can be negatively impacted as a result. Chang’s group highlighted that even though they observed significant improvement in these two QOL domains, there was also a significant decline in the domains of pain, emotion, and satisfaction [ 39 ]. Similarly, a multicenter study published by Matsumoto et al [ 63 ] reported significant improvement in pulmonary function and financial subdomain postoperatively in a scoliosis-specific patient-reported outcome measure (PROM).…”

The effectiveness of growth-friendly systems in the treatment of early onset scoliosis: a systematic review

“…При этом отсутствовала выраженная положительная динамика в качестве жизни в обеих группах [12]. В остальных работах отмечаются лишь незначительные изменения в качестве жизни пациентов по данным опросников как в положительную, так и в отрицательную сторону по разным параметрам [25,27,44].…”