Abstract:Pulmonary fibrosis is a group of lung diseases characterized by scar formation and interstitial pneumonia with a mean life expectancy of 3-5 yearspost diagnosis. Risk factors for developing IPF include external (environment) and internal (genetic risk factors). The central role in the formation of fibrosis is played by the massive myofibroblasts and the excessive deposition of extracellular matrix, including collagen I type. The main approaches for PF treatment is either lung transplantation or therapeutic tre… Show more
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