Pulmonary Ferruginous Bodies in City Dwellers

Gross, Paul; deTrevïlle, Robert T. P.; Haller, M.

doi:10.1080/00039896.1969.10666827

Cited by 27 publications

(8 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Some doubt has been expressed about the prevalence of asbestos in the lungs of the general population of the industrial countries of the western world who are not occupationally exposed to asbestos. Gross, deTreville, and Haller (1969) found that they could not identify chrysotile in the core of 28 ferruginous bodies extracted from the lungs of urban dwellers not occupationally exposed to asbestos in America. Langer (1970), however, states that the analysis of a number of ferruginous bodies gave results which were consistent with magnesium-leached chrysotile.…”

mentioning

confidence: 99%

Electron microscope characteristics of inhaled chrysotile asbestos fibre

Pooley¹

1972

Occupational and Environmental Medicine

View full text Add to dashboard Cite

Pooley, F. D. (1972).Brit. J. industr. Med.,29, 146-153. Electron microscope characteristics of inhaled chrysotile asbestos fibre. Specimens from 300 lungs have been examined under the electron microscope to determine the morphology and diffraction characteristics of any chrysotile asbestos they contained. In 120 cases, material was prepared by alkali digestion and the residual dust was examined. In all cases standard 6-micron histological slides were partially ashed before the residue was transferred to the electron microscope grids. Of the 300 specimens examined, 20 came from men with prolonged industrial exposure to chrysotile, 87 from cases of mesothelioma, and the remainder from control groups drawn from rural and industrial populations. Chrysotile fibres were readily identified by the characteristic polycrystalline diffraction pattern. The hollow appearance of the single fibres and their shape and arrangement also help in the identification. Specimens from men without industrial exposure contained either single short fibres or aggregates scattered throughout the lungs. In specimens from industrially exposed men, fibres were very numerous and found as strands of single fibres mainly grouped together in discrete locations. Ferruginous bodies were found rarely and only on straight fibre bundles of over several micrometers in length.

show abstract

mentioning

confidence: 99%

Electron microscope characteristics of inhaled chrysotile asbestos fibre

Pooley¹

1972

Occupational and Environmental Medicine

View full text Add to dashboard Cite

show abstract

“…The fact that bodies optically indistinguishable from asbestos bodies can be formed from fibres other than asbestos (Gross, de Treville, Cralley, and Davis, 1968) raises the possibility that at least some of the coated fibres detected in this series of lung smears contained a different type of mineral fibre and did not necessarily indicate exposure to asbestos. 'Pseudo-asbestos bodies', with a black central fibre, were specifically ignored when examining smears, but bodies derived from substances such as glass fibre, silicon carbide, filamentous aluminium silicate, and talc could be confused with coated asbestos fibres.…”

Section: Routine Necropsiesmentioning

confidence: 78%

Epidemiological and quantitative relationships between mesothelioma and asbestos on Tyneside

Ashcroft

1973

J Clin Pathol

View full text Add to dashboard Cite

Fibre counts were also performed on lung samples from 18 smear-positive and 30 smear-negative routine necropsies. Cases with numerous coated fibres in the smear gave total fibre counts similar to those of mesothelioma cases without asbestosis. Routine cases with only one fibre in the smear usually yielded only occasional fibres on analysis. Coated and uncoated fibres were found in 13 out of 30 smear-negative cases, indicating a true incidence of 56 % of exposure to asbestos in the whole necropsy series. When compared with the mesothelioma series the difference in incidence of fibres remains statistically significant.The data suggest that, on Tyneside, exposure to asbestos sufficient to cause an appreciable risk of developing mesothelioma has usually occurred through occupational exposure rather than by general environmental pollution by asbestos.Although noted independently by Weiss (1953), van der Schoot (1958), and Konig (1960), the association between exposure to asbestos and diffuse malignant mesothelioma first attracted wide attention through the publication of a series of South African cases by Wagner, Sleggs, and Marchand (1960). Subsequent comparisons between cases of this pathologically controversial condition and control patients have, with one exception (Hagerstrand, 'Present address:

show abstract

“…McVittie's datal9 9 show very clearly that lagging, using asbestos, can be a hazardous occupation. 41 diagnosed annually between 1950 and 1969. The number of claims for asbestosis has been steadily increasing, but in 1967 of 280 claimants, 112 were rejected2°.…”

Section: Medical Surveillance-historical Backgroundmentioning

confidence: 99%

The Medical Surveillance of Asbestos Workers

Lewinsohn

1972

Royal Society of Health Journal

View full text Add to dashboard Cite

Pulmonary Ferruginous Bodies in City Dwellers

Cited by 27 publications

References 4 publications

Electron microscope characteristics of inhaled chrysotile asbestos fibre

Electron microscope characteristics of inhaled chrysotile asbestos fibre

Epidemiological and quantitative relationships between mesothelioma and asbestos on Tyneside

The Medical Surveillance of Asbestos Workers

Contact Info

Product

Resources

About