Pulmonary Endarteritis and Subsequent Pulmonary Embolism Associated with Clinically Silent Patent Ductus Arteriosus

Onji, Keiichi; Matsuura, Wataru

doi:10.2169/internalmedicine.46.0215

Cited by 19 publications

(20 citation statements)

References 10 publications

(13 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Small PDAs represent 3% of these cases. Up to 0.5% of patients with an innocent murmur have a small PDA 41. The definition of a small PDA has not been well established.…”

Section: Resultsmentioning

confidence: 99%

Controversies in the definition and management of insignificant left-to-right shunts

Cantinotti

Assanta

Murzi

et al. 2013

Heart

View full text Add to dashboard Cite

Haemodynamically insignificant left-to-right shunts are frequently discovered when screening for congenital heart disease, resulting in significant economic and psychosocial impact. A literature search was performed within the National Library of Medicine using the keywords small/insignificant/silent atrial septal defect (ASD), ventricular septal defect (VSD), patent ductus arteriosus (PDA) and patent foramen ovale (PFO). The search was refined by adding the keywords definition, classification and follow-up. Our analysis revealed significant heterogeneity in the evaluation and management of innocent left-to-right shunts. The definitions for small defects vary greatly, making it difficult to distinguish between physiologic and pathologic lesions (eg, a PFO vs a true ASD). Most small defects will partially or completely resolve spontaneously early in life. If spontaneous resolution does not occur, the risk for long-term complications (such as embolic events and endocarditis) is low but poses several practical and ethical issues: immediate discharge versus long-term follow-up, duration and frequency of follow-up, and content and method of discussions with the parents. Additionally, there is controversy pertaining to treatment for PDAs and VSDs, particularly among interventional cardiologists, even though risk/benefit analyses are lacking. Standards and guidelines using consensus opinion for the management of insignificant left-to-right shunts are needed to address the heterogeneity in diagnosis and management as well as use of resources, ethical and psychosocial issues.

show abstract

“…Small PDAs represent 3% of these cases. Up to 0.5% of patients with an innocent murmur have a small PDA 41. The definition of a small PDA has not been well established.…”

Section: Resultsmentioning

confidence: 99%

Controversies in the definition and management of insignificant left-to-right shunts

Cantinotti

Assanta

Murzi

et al. 2013

Heart

View full text Add to dashboard Cite

show abstract

“…Other findings are observed: renal dysfunction, systemic and pulmonary embolism [9,10]. So the treatment in some elderly people are conservative, due to associated diseases and high surgical risk [6,8,11].…”

Section: Discussionmentioning

confidence: 99%

Tratamento cirúrgico da persistência do canal arterial na população adulta

Jatene

Abuchaim

Tiveron³

et al. 2011

Rev Bras Cir Cardiovasc

View full text Add to dashboard Cite

show abstract

“…A few cases of a PDA accompanied by pulmonary endarteritis, with or without subsequent pulmonary infiltrations, have been reported [5][6][7][8][9][10][11]. Blood cultures in these case reports grew Gamella species, group D Streptococcus, Streptococcus mitis, S. capitis, S. millei, and S. viridans.…”

Section: Discussionmentioning

confidence: 99%

“…Whether diabetes is an extra risk factor for infective endarteritis is unsure. However, a case with the combination diabetes, PDA, and infective pulmonary endarteritis with subsequent pulmonary infiltrates has been described previously [5].…”

Section: Discussionmentioning

confidence: 99%

A turbulent cause of bilateral pneumonia

Bathoorn

Heitbrink

Reichert

et al. 2009

European Respiratory Journal

View full text Add to dashboard Cite

A 62-yr-old female presented with complaints of progressive chest pain, increasing in severity with inspiration, a productive cough and fever for 2 days. Moreover, she had lost 12 kg in weight in the last 3 months and was experiencing night sweats. During this period, she had a folliculitis in her axilla. Her medical history yielded diabetes mellitus type II, hypertension and anaemia. Transthoracic echocardiography, performed 4 years ago, had shown flow abnormalities in the pulmonary artery and left ventricular volume overload. The patients' medication included metformin, insulin, hydrochlorothiazide, simvastatin, metoprolol, ferrofumerate and vitamin B.On physical examination, a pale and cachectic patient was seen. Her body temperature was 39uC, with a heart rate of 104 beats?min -1 , respiratory rate of 20 breaths?min -1 and blood pressure of 160/65 mmHg. Chest auscultation revealed normal breath sounds, a 2/6 systolic murmur in the right parasternal area and a 1/6 continuous murmur in the left parasternal area. Otherwise, physical examination was normal.An overview of investigations is presented in table 1. A chest radiograph was performed upon admission ( fig. 1) and a contrast-enhanced computed tomography (CT) scan was performed before and after treatment (figs 2 and 3, respectively). A CT scan was also obtained in the parenchymal setting ( fig. 4).

show abstract

Pulmonary Endarteritis and Subsequent Pulmonary Embolism Associated with Clinically Silent Patent Ductus Arteriosus

Cited by 19 publications

References 10 publications

Controversies in the definition and management of insignificant left-to-right shunts

Controversies in the definition and management of insignificant left-to-right shunts

Tratamento cirúrgico da persistência do canal arterial na população adulta

A turbulent cause of bilateral pneumonia

Contact Info

Product

Resources

About