Pulmonary embolism with chronic obstructive pulmonary disease

Yang, Ruohan; Liu, Guiqing; Deng, Chaosheng

doi:10.1016/j.cdtm.2021.04.001

Cited by 5 publications

(1 citation statement)

References 85 publications

(137 reference statements)

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“…In addition, these cytokines lead to local hypercoagulation by inhibiting plasminogen activators and reducing the brinolytic potential. Growth differentiation factor 15 is one of the biomarkers of COPD, which is related not only to the severity of thrombosis in deep venous thrombosis but also to the increased incidence of PE [33] . In addition, under certain conditions, one disease may increase the risk or severity of the other, such as NTM-PD, which is a risk factor for chronic pulmonary aspergillosis [34] .…”

Section: Discussionmentioning

confidence: 99%

Comorbidities contributing to high-cost hospital care for patients with COPD exacerbation

Wang

Shi

et al. 2023

Preprint

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Objective Although comorbidities are prevalent in chronic obstructive pulmonary disease (COPD) patients, little is known about the impact of comorbidities on hospitalization costs for COPD in Chinese hospitals. This study aimed to evaluate the impact of comorbidities on hospital costs in patients with COPD.Methods We conducted a real-world, retrospective, observational study. Patients with the major discharge diagnosis of COPD at the First Affiliated Hospital of Guangzhou Medical University between December 2013 and December 2020 were enrolled. Demographic and clinical parameters were sourced from hospital data and medical records. The top 20% of patients by cost were included in the high-cost group. Univariate and multivariate analyses were used to determine the comorbidities associated with hospitalization costs. A comorbidity network was built to complement and extend the results of the multivariate analysis.Results In total, 75.7% of COPD patients had comorbidities, and the number of comorbidities had an impact on the hospitalization cost. The results of multivariate analysis showed that the comorbidities contributing to hospital costs were pulmonary embolism, sick sinus syndrome, pneumomycosis, lymphoma, lung cancer, venous thromboembolism, aneurysm, cerebrovascular disease, chronic kidney disease, heart failure, diabetes, arteriosclerosis, obstructive sleep apnea-hypopnea syndrome, and fatty liver. The results of the comorbidity network analysis were consistent with those of the multivariate analysis.Conclusion The comorbidities can influence the burden of care for patients with COPD. Therefore, attention should be paid to early risk assessment and long-term interventions for these comorbidities in COPD patients.

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Section: Discussionmentioning

confidence: 99%

Comorbidities contributing to high-cost hospital care for patients with COPD exacerbation

Wang

Shi

et al. 2023

Preprint

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Evaluation of Four Validated Risk Scores to Predict Outcomes in Hispanic Patients With Acute Pulmonary Embolism

Murguia,

Segovia,

Ayvali

et al. 2024

Angiology

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Risk stratification plays an essential role in the management of acute pulmonary embolism (PE). Several risk scores have been studied to support risk stratification and management. While ethnic differences in acute PE risk factors exist, current risk scores lack validation for Hispanic patients. Therefore, the present study retrospectively investigated the performance of the pulmonary embolism severity index (PESI), simplified PESI (sPESI), the European Society of Cardiology risk assessment (ESC), and the Bova score, to predict 30-day mortality in Hispanic patients presenting with an acute PE. Among 437 patients admitted with acute PE, 30-day mortality was 10.8%; 30-day mortality in low-risk groups ranged from 0% (sPESI, ESC) to 0.2% (PESI, Bova), and 3.0% (Bova) to 5.7% (PESI) in the highest risk groups, respectively. All four scores produced statistically significant discrimination between different risk strata. However, no single scoring system was able to identify all patients with 30-day mortality. The findings of the present study suggest that PESI, sPESI, ESC, and Bova scores provide important information about 30-day mortality in Hispanic in-patients presenting with acute PE. However, additional clinical information could further improve predictability that is not provided by a single scoring system.

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Research Progress of Acute Exacerbation of Chronic Obstructive Pulmonary Disease with Pulmonary Embolism

何¹

2023

ACM

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Pulmonary embolism with chronic obstructive pulmonary disease

Cited by 5 publications

References 85 publications

Comorbidities contributing to high-cost hospital care for patients with COPD exacerbation

Comorbidities contributing to high-cost hospital care for patients with COPD exacerbation

Evaluation of Four Validated Risk Scores to Predict Outcomes in Hispanic Patients With Acute Pulmonary Embolism

Research Progress of Acute Exacerbation of Chronic Obstructive Pulmonary Disease with Pulmonary Embolism

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