Pulmonary embolism, frostbite and high-altitude retinopathy – a combination of life- and sight-threatening vascular complications at high altitude

Abstract

The effects of high altitude on the human vascular system are well described. This case demonstrates an interesting combination of vascular complications at high altitude which were both life-and sight-threatening. In May 2017, during an attempt on Mount Everest, a 58-year-old man was forced to descend from 8000 m because of adverse weather. He suffered significant frostbite of his right hand, later requiring termination of the distal phalanx of one of the affected digits. He also experienced increasing breathlessness and went on to develop pleuritic chest pain. A CT pulmonary angiogram performed upon return to sea level revealed multiple small sub-segmental pulmonary emboli. He was anticoagulated for three months and made a full recovery. The patient also reported visual loss in the left eye and on ophthalmic examination was found to have multiple retinal haemorrhages including a left macular haemorrhage, consistent with high altitude retinopathy. The retinal haemorrhages settled with conservative management. The vascular complications suffered by this patient demonstrate the potentially fatal changes that can occur at altitude. They also serve to act as a reminder for physicians, even at sea level of the potential complications in patients returning from high altitude.

Tromboembolismo pulmonar agudo en Santander

“…En segundo lugar, y además de presentar la información en términos de magnitud de incidencia y mortalidad por TEPA, el presente estudio identifica una correlación entre la altitud del municipio y la incidencia de TEPA (p= 0.01). Se ha mencionado por otros autores que la exposición a gran altitud ya sea por viajes aéreos o por ascenso a zonas de montaña, puede provocar un estado de hipercoagulabilidad que predispone a tromboembolismo venoso (19,20). Además, se han encontrado marcadas diferencias en la presentación de tromboembolismo como complicación postoperatoria cuando las cirugías se realizan en lugares de mayor altitud (21).…”