Pulmonary complications in toxic epidermal necrolysis: a prospective clinical study

Abstract

"Specific" involvement of bronchial epithelium was noted in 27% of cases and must be suspected when dyspnea, bronchial hypersecretion, normal chest X-ray, and marked hypoxemia are present during the early stages of toxic epidermal necrosis. Bronchial injury seems to indicate a poor prognosis, as mechanical ventilation was required for most of these patients and was associated with a high mortality.

Severe airflow obstruction and eosinophilic lung disease after Stevens-Johnson syndrome

“…Although rare, pulmonary complications do occur with SJS [2]. The current study presents a patient who developed persistent and severe airflow obstruction with associated eosinophilic lung micro-abscesses following an episode of SJS.…”

Study of Stevens - Johnson syndrome

“…As the days progress, these symptoms precede cutaneous manifesetations involving the Trunk and face area, erythema of buccal cavity, occular involvement followed by respiratory and gastrointestinal tracts, genitals, palms and soles are also involved [37,38]. …”

Toxic Epidermal Necrolysis (Lyell’s Syndrome)

“…), ДВС-синдром, септицемия, са-харный диабет, гепатит, эктропион, энтропион, симблефарон, птеригиум, изъязвление роговицы [11][12][13][14][15].…”