Pulmonary Collapse in Pertussis

Nicholson, David P.

doi:10.1136/adc.24.117.29

Cited by 14 publications

(3 citation statements)

References 51 publications

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“…Lower respiratory tract (including pneumonia) infection is also a risk factor: Western and Central Africa has one of the highest globally reported incidences of pneumonia in children (1 620 per 100 000 children); in a well vaccinated cohort of children from Cape Town, the incidence of LTRTI in the first 2 years of life was reported as 0.51 and 0.25 episodes per child year, respectively ( 39 , 40 ). With limited molecular characterization of bacterial and viral causes of severe LRTI, risk-stratification of those with severe infections, who may require follow-up, for example with severe adenoviral or B. pertussis infections, is not possible in SSA ( 41 ).…”

Section: Etiologymentioning

confidence: 99%

Bronchiectasis in African children: Challenges and barriers to care

et al. 2022

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Bronchiectasis (BE) is a chronic condition affecting the bronchial tree. It is characterized by the dilatation of large and medium-sized airways, secondary to damage of the underlying bronchial wall structural elements and accompanied by the clinical picture of recurrent or persistent cough. Despite an increased awareness of childhood BE, there is still a paucity of data on the epidemiology, pathophysiological phenotypes, diagnosis, management, and outcomes in Africa where the prevalence is mostly unmeasured, and likely to be higher than high-income countries. Diagnostic pathways and management principles have largely been extrapolated from approaches in adults and children in high-income countries or from data in children with cystic fibrosis. Here we provide an overview of pediatric BE in Africa, highlighting risk factors, diagnostic and management challenges, need for a global approach to addressing key research gaps, and recommendations for practitioners working in Africa.

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Section: Etiologymentioning

confidence: 99%

Bronchiectasis in African children: Challenges and barriers to care

et al. 2022

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“…Kohn, Schwartz, Greenbaum and Daly (1944) surveyed 222 cases of pertussis and commented on the frequency with which the right middle lobe was involved. Nicholson (1949) in his study of 44 patients found the right lower lobe to be affected 35 times, the left lower lobe 19 times and the right middle lobe 10 times. Lees (1950) reviewing 150 cases of pertussis found the left lower lobe was involved on 43 occasions, the right lower lobe on 31 and the right middle lobe on eight.…”

Section: Spread Of Infection In the Homementioning

confidence: 93%

An Investigation into Certain Aspects of Pertussis

Kesson¹,

Harling²

1953

Archives of Disease in Childhood

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The primary object of the present study, which was carried out at the Victoria Hospital for Children, Chelsea, was to investigate the incidence and course of the pulmonary complications which persist for more than two months after the onset of pertussis, and to determine whether these effects of whooping cough on the lung could be avoided. Pertussis is most dangerous in early life and we restricted our enquiry to children under the age of 4 years. An attempt was made to see each child approximately three months after the onset of the illness, for we considered that those patients who were likely to develop bronchiectasis would be found amongst those whose radiographs still showed pulmonary collapse at this stage.During the course of the investigation we were able to study the probable source of infection in our patients and also the spread of the disease to susceptible children in their household. PrmcedueOur patients were those who had been notified as suffering from this infection in Chelsea, Fulham and South Kensington during the period January 1 to December 31, 1951. A letter giving a brief explanation of the project was sent to the medical practitioner who had notified the case. If he agreed to the child attending the hospital for a medical examination he was asked to forward a card to the parents which gave an appointment for the visit. Some of the patients were referred by practitioners as cases of suspected pulmonary collapse before our request was received.At the first interview the history was recorded and the child examined. A chest radiograph in the antero-posterior plane was taken and a tuberculin jelly test with control was applied to the back. The mother was asked to come again with her child a week later, and if the radiograph showed any abnormality further films were then taken. The medical practitioner was notified of the results of the examination, and patients requiring further attention were observed until recovery was complete.

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“…των βρογχεκτασιών στο κατώτερο πνευμονικό πεδίο53 . Ο κοκκύτης σε περίπτωση που επιπλακεί με νεκρωτικού τύπου πνευμονία έχει αυξημένες πιθανότητες δημιουργίας βρογχεκτασιών στην ενήλικη ζωή54 . Οι μικροβιακές πνευμονίες που οφείλονται στον χρυσίζοντα σταφυλόκοκκο55 , την Klebsiella pneumoniae56 και την Pseudomonas aeruginosa57 αφήνουν το αποτύπωμα τους προς τη γένεση των βρογχεκτασιών.…”

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Μη Επεμβατική Αξιολόγηση Της Φλεγμονής Σε Βρογχεκτασίες

Tsikrika¹,

Τσικρικά²

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Η μη επεμβατική αξιολόγηση της φλεγμονής των αεραγωγών μπορεί να δώσει σημαντικές πληροφορίες για την θεραπευτική αντιμετώπιση ασθενών με νοσήματα του αναπνευστικού. Μέσω της μέτρησης φλεγμονωδών κυττάρων και μεσολαβητών στο υπερκείμενο των προκλητών πτυέλων (κυτταροκίνες, πρωτεΐνες, ηωσινοφιλικές πρωτεΐνες) δύναται να εκτιμηθεί ο βαθμός φλεγμονής και αναδιαμόρφωσης των αεραγωγών. Η ευρεία εφαρμογή της πρόκλησης πτυέλων στο άσθμα και ΧΑΠ έχει δώσει πληροφορίες για τη σχέση πνευμονικής λειτουργίας και φλεγμονής των αεραγωγών, ενώ παράλληλα έχει προτείνει νέους φαινότυπους με διαφορετική απάντηση στη θεραπεία. Παρόλα αυτά, λίγα δεδομένα υπάρχουν για τη χρησιμότητά της μη επεμβατικής αξιολόγησης της φλεγμονής σε ασθενείς με βρογχεκτασίες υπό σταθερές συνθήκες.

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Pulmonary Collapse in Pertussis

Cited by 14 publications

References 51 publications

Bronchiectasis in African children: Challenges and barriers to care

Bronchiectasis in African children: Challenges and barriers to care

An Investigation into Certain Aspects of Pertussis

Μη Επεμβατική Αξιολόγηση Της Φλεγμονής Σε Βρογχεκτασίες

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