Pulmonary coccidioidomycosis acquired during travel—a diagnostic and therapeutic challenge

Gino‐Moor, Sharon; Paz, Alona; Pick, Neora; Potasman, Israel

doi:10.1016/s1477-8939(03)00011-5

Cited by 3 publications

(2 citation statements)

References 16 publications

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“…In conclusion, when solitary pulmonary nodules are observed in smoking patients, malignancy should always be excluded [4,5] . Medical history, including recent travel history, may add valuable information to the final diagnosis, especially when rarely observed, imported infections, like coccidioidomycosis, present as a solitary pulmonary nodule…”

Section: Discussionmentioning

confidence: 91%

“…Diagnosis is made by histopathological examination and culture of biopsy specimens or by serologic testing [2,3,5] . Antifungal treatment may consist of an azole agent or amphotericin B, depending on the clinical manifestations and the immune status of the patient [2,4,5] . When a surgically completely resected nodule is identified as a coccidioidal infection, the prognosis is very favorable and antifungal therapy is unnecessary.…”

Section: Discussionmentioning

confidence: 99%

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Persistent Cough in a Young Smoker

Himpe¹,

Verbeken²,

Goegebuer³

et al. 2009

Respiration

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Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Persistent Cough in a Young Smoker

Himpe¹,

Verbeken²,

Goegebuer³

et al. 2009

Respiration

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Disseminated coccidioidomycosis in immunocompetent patients in non-endemic areas: a case series and literature review

Guo

Ruan

Jin

et al. 2022

Eur J Clin Microbiol Infect Dis

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Cold subcutaneous abscesses as the first manifestation of disseminated coccidioidomycosis in an immunocompromised host

et al. 2015

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Coccidioidomycosis is an endemic fungal infection in the southwestern USA and northern Mexico. It is caused by Coccidioides immitis and C. posadasii. This infection occurs due to the inhalation of airborne arthroconidia, causing a mild pulmonary infection, but most cases are asymptomatic. Disseminated coccidioidomycosis (DC) is a rare entity occurring in less than 1% of all cases, usually in immunocompromised patients, and it carries high risks of morbidity and mortality. The skin is one of the most frequently affected organs and in some cases cutaneous lesions may be the first or only sign of infection. A wide spectrum of clinical lesions may develop, including cold abscess. In immunocompromised hosts, DC represents a diagnostic and therapeutic challenge. Treatment is based on antifungal drugs, such as amphotericin B and azoles, administered for long periods of time and under close follow up to monitor the treatment response and to detect relapse. In the following case report, we present a 35-year-old male patient with systemic lupus erythematosus under immunosuppressive therapy who presented with cold subcutaneous abscesses as the first sign of DC.

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Pulmonary coccidioidomycosis acquired during travel—a diagnostic and therapeutic challenge

Cited by 3 publications

References 16 publications

Persistent Cough in a Young Smoker

Persistent Cough in a Young Smoker

Disseminated coccidioidomycosis in immunocompetent patients in non-endemic areas: a case series and literature review

Cold subcutaneous abscesses as the first manifestation of disseminated coccidioidomycosis in an immunocompromised host

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