Pulmonary blastomas

Spencer, Herbert R.

doi:10.1002/path.1700820119

Cited by 180 publications

(67 citation statements)

References 3 publications

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“…Pulmonary blastomas were designated 'embryomas' by Barnard in 1952 (2) and in 1961 spencer recategorised this neoplasm as a pulmonary blastoma (20) 10,15). Only the mesenchymal form called pleuropulmonary blastoma is observed in childhood (18).…”

Section: █ Discussionmentioning

confidence: 99%

Biphasic pulmonary blastoma associated with cerebral metastasis

Kılıç¹,

Yilmaz²,

Tepeoğlu³

et al. 2014

Turkish Neurosurgery

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Section: █ Discussionmentioning

confidence: 99%

Biphasic pulmonary blastoma associated with cerebral metastasis

Kılıç¹,

Yilmaz²,

Tepeoğlu³

et al. 2014

Turkish Neurosurgery

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“…Different subtypes can be classified and they vary in their age distribution, peaking in childhood before 10, and at 40 or 70 years of age [2,3]. One subgroup of the sarcomatoid carcinomas family, the pulmonary blastomas, has been regarded as the pulmonary counterpart of primitive malignant tumors of other organs [4,5]. In 1988, the pleuropulmonary blastoma (PPB) found in children was differentiated from the classic adult type pulmonary blastoma by its pathologic features like primitive blastoma and sarcoma without carcinomatous components [6].…”

Section: Introductionmentioning

confidence: 99%

Pancreatic metastasis of a pleuropulmonary blastoma in an adult

et al. 2000

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SummaryPleuropulmonary blastoma (PPB) is a rare dysontogenetic tumor that usually develops in the first decade of life and has been recognized as a distinct clinico-pathological entity different from the ordinary pulmonary blastoma of adulthood. Since the tumor grows aggressively and tends to metastasize early, physicians have to be aware of late onset of symptoms and uncommon manifestations. We report a case of PPB in a young adult and its recurrence in the pancreas after primary surgical treatment and adjuvant chemotherapy. Keeping in mind the moderate prognosis of PPB in children, accurate assessment and treatment of PPB require a team approach of oncology, radiology and surgery to establish new therapeutic guidelines in the future.

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“…Spencer [8] termed the expression "pulmonary blastoma" in analogy to other embryonic tumors like nephroblastoma and tial biopsy followed by preoperative chemotherapy and delayed surgical excision may improve results.…”

Section: Pathologymentioning

confidence: 98%

Pleuro‐pulmonary blastoma: A case report and review of the literature

Schmaltz

Sauter

Opitz

et al. 1995

Med. Pediatr. Oncol.

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Pleuro-pulmonary blastoma is a rare malignant lung tumor in children and distinct from ordinary pulmonary blastoma of adulthood. Combination chemotherapy plays an important role in the treatment of this tumor, but so far no attempt of high dose chemotherapy with subsequent bone marrow or blood stem cell transplantation has been published. The case is reported of a 2-year-old boy with pleuro-pulmonary blastoma who achieved partial remission with conventional chemotherapy and surgery. Subsequent administration of high dose melphalan, etoposide, and carboplatin, followed by autologous blood stem cell transplantation resulted in a 3-month disease-free interval but did not prevent eventual local recurrence, leading to death within a few weeks. Clinical presentation, pathology, management, and prognosis are discussed and the literature reviewed.

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Pulmonary blastomas

Cited by 180 publications

References 3 publications

Biphasic pulmonary blastoma associated with cerebral metastasis

Biphasic pulmonary blastoma associated with cerebral metastasis

Pancreatic metastasis of a pleuropulmonary blastoma in an adult

Pleuro‐pulmonary blastoma: A case report and review of the literature

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