Pulmonary Aspergillosis: A Review and a Description of Three New Cases

Macartney, James N.

doi:10.1136/thx.19.4.287

Cited by 29 publications

(17 citation statements)

References 58 publications

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Section: Course Of Diseasementioning

confidence: 99%

“…Aspergillomas are thought usually to arise in pre-existing lung cavities or necrotic lesions. Small fungal masses have, however, been demonstrated radiographically in bronchiectatic sacs (Vantrappen, Simons, Woestijne, and Gyselen, 1959), enlargement of aspergillomas and their cavities is well documented (Golberg, 1962;Macartney, 1964), and it is probable that they r*zsult from localized f,ungal growth in any poorly drained lung space (Pesle and Monod, 1954;Segretain, 1962;Villar et al, 1962). I should like to express my gratitude to all who have helped in the preparation of this paper: to Mary P. English for the mycological studies and for her continued encouragement; to Dr. Peter Watts for his assistance in the review of the radiographs; to Dr. J. E. G. Pearson and all the other physicians, surgeons, and general practitioners who have encouraged me to study patients under their care, …”

Section: Course Of Diseasementioning

confidence: 99%

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Allergic aspergillosis: review of 32 cases

Henderson¹

1968

Thorax

137

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Section: Course Of Diseasementioning

confidence: 99%

Section: Course Of Diseasementioning

confidence: 99%

Allergic aspergillosis: review of 32 cases

Henderson¹

1968

Thorax

137

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“…The immunocompromising conditions reported include diabetes mellitus, malnutrition, old age, alcoholism, COPD, connective tissue disorder, radiation therapy, HIV infection, non‐tuberculous mycobacterial infection(NTM) and low‐dose corticosteroid therapy 7 . Steroid therapy (dose as low as 5–20 mg every other day) and recent influenza infection 11 have been implicated as predisposing factors for this disease. Inhalation of Aspergillus spores is thought to lead to colonisation of respiratory tract, even in health.…”

Section: Discussionmentioning

confidence: 99%

COVID‐19‐associated subacute invasive pulmonary aspergillosis

Swain

Goel

Sarda

et al. 2021

Mycoses

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Background Though invasive pulmonary aspergillosis is a well known complication of COVID‐19 pneumonia, indolent forms of aspergillosis have been rarely described. Methods We prospectively collected the clinico‐radio‐microbiological data of 10 patients of subacute invasive pulmonary aspergillosis (SAIA), who presented to our hospital with recent history of COVID‐19 pneumonia along with cavitary lung disease, positive IgG (against Aspergillus) with or without positive respiratory samples for Aspergillus spp. Result The mean age of presentation of SAIA was 50.7 ± 11.8 years. All the patients had recently recovered from severe COVID‐19 illness with a mean duration of 29.2 ± 12 days from COVID‐19 positivity. Cough was the predominant symptom seen in 8/10 (80%) patients followed by haemoptysis. 7/10 (70%) patients were known diabetic. While serum galactomannan was positive in 5/9 patients (55.5%), fungal culture was positive in 2/7 patients (28.5%) and polymerase chain reaction (PCR) for Aspergillus was positive in three patients. Eight (80%) patients presented with a single cavitary lesion; pseudoaneurysm of pulmonary artery was seen in two patients and post‐COVID‐19 changes were seen in all patients. All patients were treated with voriconazole, out of which four (40%) patients died during the follow‐up period. Conclusion SAIA should be considered in the differential diagnosis of cavitating lung lesions in patients with recent history of COVID‐19 in the background of steroid use with or without pre‐existing diabetes.

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“…Mycetomata, however, are usually thinwalled (Levin, 1956;Goldberg, 1962), unlike the present lesion, which had a thick irregular wall. They tend to be apical in position but may be situated adjacent to the mediastinum (Macartney, 1964). Hydatid cysts which have undergone partial rupture may sometimes present with a thin translucent crescent due to air between the pericyst and endocyst (Barrett and Thomas, 1952;Latham, 1953;Borrie, 1962), but they usually have well-defined margins.…”

Section: The Endobronchial Teratomamentioning

confidence: 99%

Endobronchial teratoma associated with bronchiectasis and bronchiolectasis

Bateson¹,

Hayes²,

Woo-Ming³

1968

Thorax

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A teratoma in a young West Indian of Negro race is reported. The teratoma presented radiologically in the left upper lobe as an ill-defined shadow which contained a crescent-shaped translucent area and simulated a mycetoma. In addition, the left lung showed widespread nodular shadows. The left lung was resected and the teratoma was found to be endobronchial in position. This is a very rare site for a teratoma as only one of the 15 previously reported intrapulmonary teratomata may have been endobronchial. The remainder of the left lung remote from the tumour showed generalized bronchiectasis both radiologically and pathologically. The bronchiectasis was of follicular type and in addition there was widespread bronchiolectasis. The inflammatory reaction associated with the latter was responsible for the nodular shadows. The significance of these changes in relation to the teratoma is discussed.

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Pulmonary Aspergillosis: A Review and a Description of Three New Cases

Cited by 29 publications

References 58 publications

Allergic aspergillosis: review of 32 cases

Allergic aspergillosis: review of 32 cases

COVID‐19‐associated subacute invasive pulmonary aspergillosis

Endobronchial teratoma associated with bronchiectasis and bronchiolectasis

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