Pulmonary aspergilloma with prominent oxalate deposition

Limaïem, Faten; Blibech, H.; Bouhajja, Leila; Farhat, Leïla Ben; Louzir, B.

doi:10.1002/ccr3.6667

Cited by 1 publication

(1 citation statement)

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“…18 37 38 Depending on the species of Aspergillus accounting for the lesion, the Splendore–Hoeppli phenomenon/material and generation of calcium oxalate crystals (especially if Aspergillus niger is the cause) within the fungus ball may occasionally be seen. 37 39 When diagnosing single aspergillomas, the walls of the surrounding cavity must be carefully examined in order to distinguish aspergillomas from SAIA (formerly known as CNPA), in which local tissue invasion of the lung parenchyma is seen, without the presence of angioinvasion. 18 Due to the high oxygen-tension within the airways, fungus balls may contain fruiting bodies ( Fig.…”

Section: Aspergillomasmentioning

confidence: 99%

Pathological Diagnosis of Pulmonary Aspergillosis

Jensen,

Becker

2024

Semin Respir Crit Care Med

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Pulmonary aspergillosis constitutes an increasingly prevalent and potentially fatal complex of mycotic diseases, caused by different species of Aspergillus. The broad spectrum of pathological manifestations associated with pulmonary aspergillosis necessitates a differentiation of commensalism from saprophytic colonization, hypersensitivity reactions, and true invasive infections, which highlights the importance of histopathology as a gold standard in a diagnostic setting. For the past decades, changes in terminology and contradicting contributions from different diagnostic disciplines have made the classification of pulmonary aspergillosis rather confusing. This review offers a categorization of aspergillosis lesions based on what can be histopathologically identified and distinguished, differentiating between acute invasive infection and forms of subacute, chronic, and allergic diseases and coinfections, and summarizes important manifestations of lesions associated with the different forms of pulmonary aspergillosis.

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