Pulmonary and paradoxical coronary embolism with a patent foramen ovale

Falcetta, Giosuè; Scioti, Giovanni; Barzaghi, C; Bortolotti, Uberto

doi:10.1177/0218492318777394

Cited by 7 publications

(3 citation statements)

References 9 publications

(9 reference statements)

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“…Several previous studies 31,32 have shown that smoking is closely related to atherosclerosis and thrombosis. Long-term heavy smoking can damage alveolar epithelial cells, resulting in a reduction in the amount of oxygen diffused.…”

Section: Discussionmentioning

confidence: 96%

Risk factors for acute pulmonary embolism in patients with off-pump coronary artery bypass grafting: implications for nursing

Zhou

Cao

et al. 2020

J Int Med Res

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Objective Acute pulmonary embolism (APE) is a serious complication after off-pump coronary artery bypass grafting (OPCABG). We aimed to analyze the risk factors for APE in patients with OPCABG. Methods In this retrospective, observational study, patients with OPCABG who were treated in our hospital from 1 January 2018 to 31 March 2020 were included. The basic characteristics of patients and results of preoperative laboratory examinations were collected and analyzed. Results A total of 707 patients with OPCABG were included and the incidence of APE was 3.21%. Left ventricular ejection fraction (LVEF), a history of smoking, number of bypass grafting, duration of surgery, and age were significant risk factors for APE in patients with OPCABG. The areas under the curves of LVEF, number of bypass grafting, duration of surgery, and age were 0.773, 0.759, 0.738, and 0.723, respectively. The cutoff values of LVEF, number of bypass grafting, duration of surgery, and age were 59.84, 3.18, 237.42, and 73.28, respectively. Conclusions LVEF, a history of smoking, number of bypass grafting, duration of surgery, and age may be risk factors for APE in patients with OPCABG. Early measures should be taken to target these risks to prevent APE.

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Section: Discussionmentioning

confidence: 96%

Risk factors for acute pulmonary embolism in patients with off-pump coronary artery bypass grafting: implications for nursing

Zhou

Cao

et al. 2020

J Int Med Res

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“…Aspiration thrombectomy; Intracoronary heparin and abciximab; Antiplatelet treatment not mentioned Pul: Lifelong anticoagulant (Warfarin) PFO closure: Multidisciplinary discussion not recommend 4 Smith et al [ 10 ] 69 years female STEMI (inferior wall); PE; PFO; Acute RV Failure C: Occlusion of PD and PL; Aspiration thrombectomy and balloon dilation; Oral aspirin Pul: Pulmonary angiography, interventional clot fragment and aspiration; and intra-arterial thrombolysis; Long-term anticoagulant (Warfarin) PFO closure: No 5 Knobloch et al [ 13 ] 38 years male STEMI (inferior wall); PE and DVT. Embolic occlusion of the left popliteal artery and left carotid artery; PFO C: Normal coronary angiogram Pul: Not mentioned PFO closure: Yes, transcatheter Others: Left popliteal: Embolus removal with Fogarty catheter; Left carotid embolus: surgery 6 Haghi et al [ 14 ] 61 years female NSTEMI; PE; PFO C: Balloon angioplasty (OM) and oral Aspirin Pul: Long-term anticoagulant (Warfarin) PFO closure: No 7 Falcetta et al [ 15 ] 68 years male STEMI (inferior wall); PE and DVT; PFO. C: Aspiration thrombectomy (RCA) Pul: Surgical removal of embolus in pulmonary trunk; Long-term anticoagulant (Specific drug not mentioned) PFO closure: Surgery removal of the worm-shaped embolus (13 cm) and PFO surgical sutured 8 Uchida et al [ 16 ] 59 yrs male STEMI (inferior wall); PE; PFO; AF.…”

Section: Discussionmentioning

confidence: 99%

Concomitant acute myocardial infarction and acute pulmonary embolism caused by paradoxical embolism: a case report

Chen

et al. 2021

BMC Cardiovasc Disord

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Background Due to its low incidence and diverse manifestations, paradoxical embolism (PDE) is still under-reported and is not routinely considered in differential diagnoses. Concomitant acute myocardial infarction (AMI) and acute pulmonary embolism (PE) caused by PDE has rarely been reported. Case presentation A 45-year-old woman presented with acute chest pain and difficulty with breathing. Multiple imaging modules including ECG, echocardiography, emergency cardioangiogram (CAG), and CT angiography of the pulmonary arteries showed acute occlusion of the posterolateral artery and acute PE. After coronary aspiration, no residual stenosis was observed. One month later, a bubble study showed inter-atrial communication via a patent foramen ovale (PFO). The AMI in this patient was finally attributed to PDE via the PFO. PFO closure was performed, and long-term anticoagulation was prescribed to prevent recurrent thromboembolic events. Conclusions PDE via PFO is a rare etiology of AMI, especially in patients with concomitant AMI and PE. Clinicians should be vigilant of this possibility and close the inter-atrial channel for secondary prevention.

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“…По данным Шведского регистра, они встречались примерно у 10% у пациентов с ТЭЛА. При этом у 36% пациентов с выявленным тромбом в правом предсердии находились признаки ТЭЛА [7]. Как уже упоминалось выше, существует несколько подходов к лечению тромбоза предсердий: механическое удаление и медикаментозное лечение (тромболизис или антикоагулянт) [8].…”

Section: что делать с тромбом в полости сердца?unclassified

Clinical case of a paradoxical embolism that caused an acute myocardial infarction after deep vein thrombosis

et al. 2020

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Paradoxical thromboembolism due to the presence of an patent foramen ovale (PFO) is a rather rare phenomenon, especially when an embolism results in acute myocardial infarction (MI). The presented clinical case of the paradoxical embolism is interesting for several reasons: firstly, the patient's primary disease was deep vein thrombosis (DVT) and pulmonary artery thromboembolism (PATE); secondly, apparently, it was due to PATE and the subsequent overload of the right side of the heart that thelatent embolism became apparent; thirdly, the paradoxical embolism was apparently caused by the fragments of alarge thrombus stuck in PFO, fourthly, the current clinical situation was ambiguous with respect to medical decisions, primarily concerning antithrombotic therapy.

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Pulmonary and paradoxical coronary embolism with a patent foramen ovale

Cited by 7 publications

References 9 publications

Risk factors for acute pulmonary embolism in patients with off-pump coronary artery bypass grafting: implications for nursing

Risk factors for acute pulmonary embolism in patients with off-pump coronary artery bypass grafting: implications for nursing

Concomitant acute myocardial infarction and acute pulmonary embolism caused by paradoxical embolism: a case report

Clinical case of a paradoxical embolism that caused an acute myocardial infarction after deep vein thrombosis

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