Pulmonale Manifestationen bei Erkrankungen des rheumatischen Formenkreises

Abstract

Collagen based vascular diseases with pulmonary involvement comprise rheumatoid arthritis, systemic lupus erythematosus, progressive systemic sclerosis, dermatomyositis and polymyositis, ankylosing spondylitis, Sjögren's syndrome, and mixed connective tissue diseases. The different characteristics of pulmonary involvement are described. In such circumstances, early recognition of lung involvement is of considerable significance and the relationship to the corresponding disease has to be made. Frequently unrecognised pulmonary involvement ends up as fibrosis with irreversible deficits in respiratory function.

Restrictive Chest Wall Disorders

“…In some areas, AS is the second most common inflammatory joint disease, with unlikely claims of incidence as high as 0.37% (in Italy) and even 1.8% (in Germany) of the population. 148,149 In 90% of AS patients human leukocyte antigen HLA-B27 histocompatibility antigen is present 149 ; 20% of all persons having this antigen get AS in their lifetime. 150 The disease occurs mainly in men; in women it is rare and less severe.…”

“…The prevalence of subclinical lung involvement varies, mainly depending on the imaging method used. 149,150,[155][156][157][158][159] When fibrobullous disease is present, it can be complicated by mycetoma, non-TB mycobacterial infection, bronchocentric granulomatosis, pleural effusion, spontaneous empyema, or spontaneous pneumothorax. 150,154 Pulmonary Physiology Considerable work has been done studying pulmonary physiology in ankylosing spondylitis.…”