Pulchinenoside B4 ameliorates oral ulcers in rats by modulating gut microbiota and metabolites
Dewei Luo,
Li Yan,
Zhujun Wang
et al.
Abstract:Pulchinenoside B4, a natural saponin monomer from the Pulsatilla plant, plays an important role as an immunomodulator in the treatment of acute inflammation. Oral ulcer (OU) is a common ulcerative injury disease that occurs in the oral mucosa, including mucosal ulceration and abnormalities of lips and tongue. A close correlation exists between gut microbiota and circulating metabolites in patients with OU. However, the correlation between gut microbiota and serum metabolomics is not clear. Therefore, this stud… Show more
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