Publisher Correction: Sex dependent effects of post-natal penicillin on brain, behavior and immune regulation are prevented by concurrent probiotic treatment

Abstract

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Antibiotic-induced gut dysbiosis and cognitive, emotional, and behavioral changes in rodents: a systematic review and meta-analysis

“…Antibiotics were administered to mice in the early postnatal phase of life in seven articles (16 populations; Table 3 ). Kayyal et al (2020) reported that oral penicillin administration led to a decrease in sociability but not anxiety in male mice without any behavioral changes in female mice 21 days post-antibiotic intake. Orally administered ampicillin and vancomycin alone caused significant increase in anxiety and decrease in social novelty, spatial cognition and sociability (except in ampicillin-treated mice) 14 days after cessation of treatments ( Liu et al, 2022 ).…”

“…However, these studies differed in the dosage of ampicillin used. Gut Firmicutes levels increased after penicillin V administration only in 14 days old male mice, but not in females ( Kayyal et al, 2020 ). Sex-related differences in response to the same antibiotics were also reported by Lynch et al (2023) .…”

“…. (2016);Kayyal et al (2020);Wang et al (2020a,b);Li et al . (2015);Guida et al (2018);Jang et al (2018); Kayyal et al(2020); Ray et al (2021) No change 15 Hoban et al (2016); Champagne-Jorgensen et al (2020); Kayyal et al (2020); Leigh et al (2020); Zhao et al (2020); Keogh et al (2021); Ray et al (2021); Li et al (2022); Zhang et al (2022); Sun et al (2023) Corticosterone (circulating) Increase 5 Jang et al (2018); Zhao et al (2020); Ruiz-González et al (2022); Sarkar et al (2022); Sun et al (2023) Decrease 2 Li et al (2022); Zhang et al (2022) No change 6 Desbonnet et al (2015); Hoban et al (2016); Li et al (2022); Yu et al (2022)…”