Publication bias does not play a role in the reporting of the results of endoscopic ultrasound staging of upper gastrointestinal cancers

Abstract

No evidence was found for the selective reporting of more positive EUS results for esophageal, gastric, and pancreatic cancer staging, which suggests that publication bias was not present.

Prediction of survival in patients with oesophageal or junctional cancer receiving neoadjuvant chemoradiotherapy and surgery

“…ypN category was the most important prognostic factor in this study, confirming previous reports 42,43 , and underlining the continued significance of pN category as an important prognostic factor in the era of multimodal treatment 42 -45 . Surprisingly, cN category was an independent prognostic factor in patients treated with nCRT plus surgery, despite its relative inaccuracy 46,47 . By definition, cN category is an estimation of nodal involvement before nCRT, whereas ypN category is an estimation of nodal involvement after nCRT.…”

Residual Esophageal Cancer after Neoadjuvant Chemoradiotherapy Frequently Involves the Mucosa and Submucosa

“…Also, the alternative gold standard would be clinical staging based on EUS, which, although accepted as the most accurate clinical T-staging modality, is still considered relatively inaccurate, especially for less advanced tumors. 45 Therefore, we consider the staging method based on preypT (because of its high resolution) preferable for this study as opposed to clinical staging by EUS.…”

The emerging field of radiomics in esophageal cancer: current evidence and future potential

“…Accurate tumor staging is crucial for determining prognosis and treatment decision-making in individual patients. EUS is the current modality of choice for primary tumor staging, with reported accuracies for distinguishing T-stages of 53–94% (median, 83%) and better performance in advanced compared to early disease (63,64). Disadvantages of EUS include the invasiveness of the technique, a failure rate of 14–25% due to stenotic tumors preventing passage of the endoscope, and the strong dependence of diagnostic performance on the experience of the endoscopist (65–67).…”