Improving stroke-related knowledge may advance stroke prevention and reduce pretreatment delay and disabilities. Methods: We conducted a cross-sectional study among a representative sample of primary healthcare adult patients between January-May 2016 and used a validated Arabic questionnaire to evaluate the participants' awareness about stroke. Results: The study involved 1472 adults. Only 63.6% and 43.7% of participants correctly recognized thrombosis and hemorrhage as types of stroke. Commonly identified risk factors were hypertension)55.8%(, dyslipidemia)45.8%(, and smoking)41.9%(. Sudden severe headache)54.1%(, dizziness)51.0%(, and difficulty in speaking)44.3%(were the most frequently recognized symptoms. The most frequently reported correct responses to stroke were contacting a doctor)73.0%(, going to the hospital)67.2%(, and calling an ambulance)52.4%(. Improper responses to stroke)ignoring the condition or self-prescription(were noted in 18.8% of participants. Logistic regression revealed that physicians, nurses, friends and relatives as a source of knowledge were significantly associated with a lower insufficient knowledge of stroke symptoms and risk factors. On the other hand, women, persons above 40 years old, and married persons were significantly more prone to have insufficient knowledge about a proper response to stroke. Conclusion: Our study revealed a notable deficit of knowledge about warning symptoms, risk factors, and proper response to stroke. Health education strategies to improve stroke awareness are required and could potentially prevent and improve the outcome of stroke.