Public Knowledge and Attitudes Toward Clinical Trials in the COVID-19 Era

Patel, Eshan U.; Zhu, Xianming; Quinn, Thomas C.; Tobian, Aaron A.R.

doi:10.1016/j.amepre.2021.09.002

Cited by 3 publications

(2 citation statements)

References 9 publications

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“…In a study published in 2021 in the US, respondents (59%) identified physicians as their first source of information about clinical trials [22]. In another study conducted by the National Cancer Institute in the US, respondents identified a healthcare provider (73.3%) and patient organizations (13.5%) as their source of information about clinical trials [23].…”

Section: Discussionmentioning

confidence: 99%

Knowledge and Beliefs of Clinical Trials Among Adults in Poland

Cięszczyk,

Czech,

Gujski

et al. 2024

Preprint

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Background: Clinical trials, by contributing to the development of diagnostics and to the search for modern, more effective, and safer therapies, have become one of the most important elements of the healthcare system. The aim of this study was to assess Poles' knowledge and beliefs about clinical trials. Methods: The survey was conducted among Poles aged 18 and over with the help of external company. The questionnaire contained 22 questions, of which 13 questions concerned beliefs and attitudes towards clinical trials. Results: Data were obtained from 1079 Poles (52.6% women). Among the respondents, 86.5% were aware of clinical trials. The main source of information about clinical trials was the media (53.8%) including the Internet (32.9%) and TV (16.2%). 43.2% of respondents reported little knowledge of clinical trials, while more than three quarters (75.2%) said they would like to learn more about clinical trials. Most respondents (81.4%) agreed with the statement that participation in a clinical trial is completely voluntary, and more than half (53.7%) agreed with the statement that hospitals participating in clinical trials provide better healthcare. The statement that the results of clinical trials are made available to the public was disagreed with by 37.2% of participants. Only 30.3% of participants agreed that clinical trials should be conducted with children. Conclusions: Poles rate their knowledge of clinical trials as low and would like to learn more. To reach the largest possible group of Polish patients, parallel educational activities on multiple levels may have the best effect. Poles' knowledge of clinical trials is mainly based on commercial sources. Further studies in different groups, i.e., clinical trial patients and investigators, are needed.

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Section: Discussionmentioning

confidence: 99%

Knowledge and Beliefs of Clinical Trials Among Adults in Poland

Cięszczyk,

Czech,

Gujski

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…In a study published in 2021 in the US, respondents (59.0%) identified physicians as their first source of information about clinical trials [ 24 ]. In another study conducted by the National Cancer Institute in the US, respondents identified a healthcare provider (73.3%) and patient organizations (13.5%) as their source of information about clinical trials [ 25 ].…”

Section: Discussionmentioning

confidence: 99%

Knowledge and Beliefs about Clinical Trials among Adults in Poland: A Cross-Sectional Study

Cięszczyk,

Czech,

Pronicki

et al. 2024

Clinics and Practice

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Clinical trials, by contributing to the development of diagnostics and to the search for modern, more effective, and safer therapies, have become one of the most important elements of the healthcare system. They enable the introduction of innovative drugs and treatments that can significantly improve patients’ quality of life. Not only does this research help to understand disease mechanisms, but it also enables the personalization of therapy, which often increases the effectiveness of treatment. Public awareness of clinical trials helps build trust in science and medicine, which is fundamental to the effective functioning of the healthcare system. The aim of this study was to assess Poles’ knowledge and beliefs about clinical trials. Methods: The survey was conducted among Poles aged 18 and over with the help of an external company, Ariadna, which is an independent research panel. The questionnaire contained 22 questions, of which 13 questions concerned beliefs and attitudes towards clinical trials. Results: One thousand and seventy-nine participants took part in the study (n = 1079). The mean age of respondents was 44.96 years (SD = 16.30). Slightly more women (n = 568, 52.6%) than men (n = 511, 47.4%) took part in the study. Among the respondents, 86.5% (n = 933) were aware of clinical trials. The main sources of information about clinical trials were the media (53.8%) including the Internet (n = 355, 32.9%), TV (n = 175, 16.2%), press (n = 30, 2.8%), and radio (n = 21, 1.9%). 43.2% (n = 466) of respondents reported little knowledge of clinical trials, while more than three quarters (n = 805, 75.2%) said they would like to learn more about clinical trials. Most respondents (n = 879, 81.4%) agreed with the statement that participation in a clinical trial is completely voluntary, and more than half (n = 580, 53.7%) agreed with the statement that hospitals participating in clinical trials provide better healthcare. The statement that the results of clinical trials are made available to the public was disagreed with by 37.2% (n = 402) of participants. Only 30.3% (n = 327) of participants agreed that clinical trials should be conducted with children. Most respondents (n = 638, 59.1%) agreed with the statement that a patient in a clinical trial is insured. 48.3% (n = 521) of participants are aware that a clinical trial can be withdrawn from at any time. Conclusions: Poles rate their knowledge of clinical trials as low and would like to learn more. Poles’ knowledge of clinical trials is mainly based on commercial sources.

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Knowledge and Attitude towards Clinical Trials among General Population of Northern Saudi Arabia during COVID-19 Era: A Cross-Sectional Study

et al. 2023

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Recruiting and retaining sufficient participants is one of the biggest challenges researchers face while conducting clinical trials (CTs). This is due to the fact of misconceptions and insufficient knowledge concerning CTs among the public. The present cross-sectional study was conducted from April 2021 to May 2022. We evaluated knowledge and attitude among 480 participants using a pretested Arabic questionnaire. The correlation between knowledge and attitude score was tested through Spearman’s correlation test, and the logistic regression test evaluated the associated factors for knowledge and attitude. Of the studied participants, 63.5% were male and belonged to the age group less than 30 years (39.6%). Nearly two-thirds (64.6%) of them had never heard of CT. More than half of the participants had poor knowledge (57.1%) and attitude (73.5%) towards CTs. Participants’ knowledge scores were significantly associated with education level (p = 0.031) and previous participation in health-related research (p = 0.007). Attitude scores were significantly related to marital status (p = 0.035) and the presence of chronic diseases (p = 0.008). Furthermore, we found a significant positive correlation between knowledge and attitude scores (p < 0.001, Spearman’s rho = 0.329). The present study revealed that most of the study population had poor knowledge and moderate attitudes towards CT. Targeted health education programs at different public places are recommended to improve the public’s knowledge of the importance of CT participation. In addition, exploratory and mixed-methods surveys in other regions of KSA is required to recognize the region-specific health education needs.

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Public Knowledge and Attitudes Toward Clinical Trials in the COVID-19 Era

Cited by 3 publications

References 9 publications

Knowledge and Beliefs of Clinical Trials Among Adults in Poland

Knowledge and Beliefs of Clinical Trials Among Adults in Poland

Knowledge and Beliefs about Clinical Trials among Adults in Poland: A Cross-Sectional Study

Knowledge and Attitude towards Clinical Trials among General Population of Northern Saudi Arabia during COVID-19 Era: A Cross-Sectional Study

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