Public acceptance of a hypothetical Ebola virus vaccine in Aceh, Indonesia: A hospital-based survey

Harapan, Harapan; Anwar, Samsul; Ferdian, Muhammad N.; Salwiyadi, Salwiyadi; Imanda, Aga Sunanda; Azhars, Roully; Fika, Dheni Fidiyah; Ilham, Darul; Timur, Arya U.; Sahputri, Juwita; Maulana, Reza; Kurniawan, Hendra; Ughasoro, Maduka Donatus

doi:10.12980/apjtd.7.2017d6-386

Cited by 6 publications

(3 citation statements)

References 25 publications

(42 reference statements)

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“…Our findings indicated that when the vaccine is provided freely, 93.3 and 67.0% of participants would like to be vaccinated if the vaccine had 95% and 50% effectiveness, respectively. The acceptance rate for the first model (i.e., 95% efficacy) is far higher compared to acceptance of other new vaccines in southeast Asia (21,22,25,34). This indicates that a majority of the general population in the country are supportive of the COVID-19 vaccine.…”

Section: Discussionmentioning

confidence: 98%

“…This vaccine development is proceeding at a fast pace; prior to March 30, 2020, two vaccine candidates had entered Phase 1 clinical trials (13) while on April 9, five vaccine candidates in total were in Phase 1 clinical trials (33). In the region of southeast Asia, studies have been conducted to assess the acceptance of a vaccine against infectious diseases (21)(22)(23)(24)(25)(26)34). This present study was conducted to understand how the COVID-19 vaccine, when available, will be accepted by the general population in Indonesia, by asking individuals about a hypothetical vaccine-an approach used in many past studies (21,26,(28)(29)(30).…”

Section: Discussionmentioning

confidence: 99%

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Acceptance of a COVID-19 Vaccine in Southeast Asia: A Cross-Sectional Study in Indonesia

Harapan

Wagner

Yufika

et al. 2020

Front. Public Health

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Introduction: Several vaccine candidates are being clinically tested in response to the 2019 coronavirus disease (COVID-19) pandemic. This study was conducted to assess the acceptance of a 50 or 95% effective COVID-19 vaccine, when it becomes available in southeast Asia, among the general population in Indonesia. Methods: A cross-sectional online survey was conducted between March 25 and April 6, 2020. Participants were asked if they would accept a free vaccine which was 95 or 50% effective. Using a logistic regression model, we assessed the associations between sociodemographic characteristics, exposure to COVID-19 information, or perceived risk of infection with acceptance of a hypothetical COVID-19 vaccine. Results: Among 1,359 respondents, 93.3% of respondents (1,268/1,359) would like to be vaccinated for a 95% effective vaccine, but this acceptance decreased to 67.0% (911/1,359) for a vaccine with 50% effectiveness. For a 95% effective vaccine, being a healthcare worker and having a higher perceived risk of COVID-19 infection were associated with higher acceptance, adjusted odds ratio (aOR): 2.01; 95%CI: 1.01, 4.00 and aOR: 2.21; 95%CI: 1.07, 4.59, respectively; compared to civil servants, being retired was associated with less acceptance (aOR: 0.15; 95%CI: 0.04, 0.63). For a 50% effective vaccine, being a healthcare worker was also associated with greater acceptance, aOR: 1.57; 95%CI: 1.12, 2.20. Conclusion: Acceptance of a COVID-19 vaccine was highly influenced by the baseline effectiveness of the vaccine. Preparing the general population to accept a vaccine with relatively low effectiveness may be difficult.

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Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Acceptance of a COVID-19 Vaccine in Southeast Asia: A Cross-Sectional Study in Indonesia

Harapan

Wagner

Yufika

et al. 2020

Front. Public Health

Self Cite

577

558

View full text Add to dashboard Cite

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“…Study participants were patients' family members who visited infection and non-infection outpatient departments. Based on the population size of Aceh in 2014, the minimum sample size required was 385 18 . To recruit the samples, four regencies were selected randomly, and both urban and suburban areas were included.…”

Section: Study Participants Sampling and Sample Sizementioning

confidence: 99%

Willingness-to-pay for a hypothetical Ebola vaccine in Indonesia: A cross-sectional study in Aceh

et al. 2023

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Background: Some Ebola vaccines have been developed and tested in phase III clinical trials. However, assessment of whether public have willingness to purchase or not, especially in unaffected areas, is lacking. The aim of this study was to determine willingness to pay (WTP) for a hypothetical Ebola vaccine in Indonesia. Methods: A cross-sectional study was conducted from 1 August to 30 December 2015 in five cities in Aceh province of Indonesia. Patients’ family members who visited outpatient departments were approached and interviewed about their sociodemographic characteristics, knowledge of Ebola, attitude towards vaccination practice and their WTP for a hypothetical Ebola vaccine. A multivariable linear regression model assessed the relationship between these explanatory variables and WTP. Results: During the study, 500 participants were approached and interviewed. There were 424 (84.8%) respondents who completed the interview and 74% (311/424) expressed their acceptance for an Ebola vaccine. There were 288 participants who were willing to pay for an Ebola vaccine (92.6% out of 311). The mean of WTP was US$2.08 (95% CI: 1.75-2.42). The final multivariable model indicated that young age, high educational attainment, working as a private employee, entrepreneur or civil servant (compared to farmers), being unmarried, and residing in a suburb (compared to a city) were associated with higher WTP. Conclusions: Although the proportion of the participants who would accept the Ebola vaccine was relatively high, the amount they were willing to pay for Ebola vaccine was very low. This finding would indicate the need of subsidies for Ebola vaccine in the country.

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Parents’ hesitancy towards vaccination in Indonesia: A cross-sectional study in Indonesia

Yufika

Wagner

Nawawi

et al. 2020

Vaccine

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Public acceptance of a hypothetical Ebola virus vaccine in Aceh, Indonesia: A hospital-based survey

Cited by 6 publications

References 25 publications

Acceptance of a COVID-19 Vaccine in Southeast Asia: A Cross-Sectional Study in Indonesia

Acceptance of a COVID-19 Vaccine in Southeast Asia: A Cross-Sectional Study in Indonesia

Willingness-to-pay for a hypothetical Ebola vaccine in Indonesia: A cross-sectional study in Aceh

Parents’ hesitancy towards vaccination in Indonesia: A cross-sectional study in Indonesia

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