Puberty in Children with Cancer

Shalet, Stephen M; Brennan, Bernadette

doi:10.1159/000058099

Cited by 10 publications

(4 citation statements)

References 27 publications

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“…Some also experience cognitive impairment which can impact on employment and educational attainment [ 25 , 26 ]. Concerns related to reduced fertility and sexual dysfunction are also prevalent among AYA cancer survivors [ 27 , 28 ].…”

Section: Introductionmentioning

confidence: 99%

Measuring the psychosocial health of adolescent and young adult (AYA) cancer survivors: a critical review

Clinton‐McHarg

Carey

Sanson‐Fisher

et al. 2010

Health and Quality of Life Outcomes

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BackgroundAdolescent and young adult (AYA) cancer survivors require psychometrically rigorous measures to assess their psychosocial well-being. Without methodologically adequate scales the accuracy of information obtained on the prevalence of needs, predictors of risk, and the potential success of any interventions, can be questioned. This review assessed the psychometric properties of measures designed specifically to identify the psychosocial health of this unique population.MethodsMedline, PsycINFO, CINAHL and EMBASE databases were searched to identify measures developed to assess the psychosocial health of AYA cancer survivors. Searches were limited to the years 1998-2008. A search of Medline revealed that the number of publications related to the assessment of psychosocial well-being in AYA cancer survivors prior to this period were minimal. The psychometric properties of identified measures were evaluated against pre-determined and generally accepted psychometric criteria including: reliability (internal consistency and test-retest); validity (face, content, construct, and criterion); responsiveness; acceptability; and feasibility.ResultsSeven quality of life measures met the inclusion criteria. No measures of unmet need were identified. All seven measures reported adequate internal consistency, face, content, and construct validity. Test-retest reliability, criterion (predictive) validity, responsiveness, acceptability, and feasibility were rarely examined.ConclusionsThere is a need to further evaluate the psychometric properties of existing quality of life measures for AYA cancer survivors. Valid, reliable, and acceptable measures which can assess the psychosocial needs of this population should also be developed.

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Section: Introductionmentioning

confidence: 99%

Measuring the psychosocial health of adolescent and young adult (AYA) cancer survivors: a critical review

Clinton‐McHarg

Carey

Sanson‐Fisher

et al. 2010

Health and Quality of Life Outcomes

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“…Cranial irradiation can damage the hypothalamic-pituitary axis, leading to gonadotropin or growth hormone deficiency at high dosages, and precocious puberty at lower dosages [34][35][36][37]. The age of pubertal onset has been shown to be particularly important in determining final height, with younger children being at greater risk of developing precocious puberty and therefore eventual shorter stature [38].…”

Section: Growthmentioning

confidence: 99%

Imaging of late complications of cancer therapy in children

et al. 2016

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Long-term survival after childhood cancer has improved dramatically over recent decades but survivors face lifelong risks of adverse health effects. Many of these chronic conditions are a direct result of previous therapeutic exposures. Compared to their siblings, survivors face a greater than 8-fold increase in relative risk of severe or life-threatening medical conditions; the most significant of these include second malignancies and cardiovascular and pulmonary diseases. Imaging can play a key role in identifying and characterizing such complications, which can be reasonably predicted with knowledge of the child's treatment. This article highlights the varied radiologic presentations and features seen in late cancer-therapy-related conditions.

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“…In younger adolescents still undergoing puberty, pubertal problems may develop because of treatment effect on the central nervous system, the hypothalamic-pituitary axis, or the gonads directly. 14 In addition, patients may have a variety of concerns about body image because of hair loss, weight gain or loss, the presence of implantable devices, and surgical scars. 15 Problems of sexual function are also noted by cancer patients and survivors, although oftentimes they are not addressed during follow-up care.…”

Section: Sexual and Reproductive Healthmentioning

confidence: 99%

Assessing and optimizing health-related quality of life during and after cancer treatment in adolescents and young adults

Szalda¹,

Kim²,

Ginsberg³

2014

COAYA

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Adolescent and young adults (AYAs) with cancer have needs unique from their pediatric or adult counterparts at diagnosis, during treatment, and throughout survivorship care. Healthcare teams may find it difficult to assess and manage the complex psychosocial needs of AYA patients, however, attention to the multi-faceted care of the AYA oncology patient may directly affect health outcomes and quality of life. Comprehensive AYA care therefore must be maximized during treatment and in transition to survivorship care by including assessments of general health, sexual health, mental health, health behaviors, and conversations concerning transition to survivorship and adulthood with AYA patients. Identifying and treating issues that arise in the AYA population may help promote adherence to treatment, engagement in follow-up care, and ultimately quality of life for this unique group of patients.

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Puberty in Children with Cancer

Cited by 10 publications

References 27 publications

Measuring the psychosocial health of adolescent and young adult (AYA) cancer survivors: a critical review

Measuring the psychosocial health of adolescent and young adult (AYA) cancer survivors: a critical review

Imaging of late complications of cancer therapy in children

Assessing and optimizing health-related quality of life during and after cancer treatment in adolescents and young adults

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