PTU-110 Elevated C reactive protein in anti-TNF-naïve patients is associated with higher remission rates: Abstract PTU-110 Table 1

Serum C-reactive Protein and CRP Genotype in Pediatric Inflammatory Bowel Disease

“…33,45 Second, we have observed, along with others, 19 that children across all IBD types differ significantly in their ability to produce a serum CRP response, even in the presence of overt clinical disease. Finally, recent evidence has suggested that adult patients with IBD with a high baseline CRP level at induction demonstrate a better primary response to biological therapies, with early normalization of CRP levels correlating with sustained long-term response 21,47 ; however, these results are variable. 4 Third, regarding cardiovascular risk and systemic lupus erythematosus, studies have suggested that failure to respond appropriately to inflammation with a rise in serum CRP may be a factor in disease pathogenesis.…”