PTU-057 LINX^®magnetic sphincter augmentation: azithromycin and high dose proton pump inhibitors can identify reversible oesophageal hypomotility

Abstract

Methods Data collection spanned 16 months (1/1/2016-30/4/ 2017) with 442 patients being identified from the Infoflex endoscopy database. Patients were enrolled if the main indication for upper gastrointestinal endoscopy was coded as 'Barrett's surveillance'. Review of histology reports, Infoflex accounts and clinical notes allowed acquisition of both 'Prague Classification' and 'Seattle Biopsy Protocol' data, alongside operator status (generalist or specialist). The relationship between type of endoscopy and compliance to techniques were assessed statistically through chi-squared independence testing. Results From 442 cases (Mean 66.2 years (Range 24-88)), compliance to both 'Prague Classification' and 'Seattle Biopsy Protocol' were 73% (322/442) and 70% (309/442), respectively. Access to specialist endoscopy was improved at 41% compared to 26% (2014)(2015). Furthermore, specialist endoscopy yielded superior adherence to both, 'Prague Classification' (87%, (157/181) v 63%, (165/261); X 2 =31.04, p<0.0001)) and 'Seattle Biopsy Protocol' (75%, (136/181) v 66%, (173/261); X 2 =4.09, p=0.0432)), compared with generalist counterparts. Conclusions Specialist endoscopy improves adherence to BSG recommendations. The introduction of dedicated specialist lists at this large teaching hospital will help to optimise surveillance further. Ultimately, future work is necessary to help identify whether this specialist service carries value for both, BO screening and outcomes related to oesophageal dysplasia and OAC.