Pterygium Removal Using a Polyethylene Glycol Hydrogel Adherent Ocular Bandage

Hirst, Lawrence W.

doi:10.1097/ico.0b013e3182847a6a

Cited by 3 publications

(4 citation statements)

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“…In the cases described herein, the sealant appeared to be easier to use, less time-consuming, and also improved patients’ symptoms postoperatively compared to either sutures or fibrin glue. In contrast, Hirst [11] noted prolonged inflammation replaced by conjunctival scarring after ReSure application to adhere conjunctival autograft to the lesion. This could be due to direct application of ReSure to cover the area of Tenon from where the donor graft was retrieved and/or using sutures to place the graft in place.…”

Section: Discussionmentioning

confidence: 99%

“…ReSure was previously used in Australia for pterygium surgery using conjunctival autograft, which resulted in prolonged inflammation and conjunctival scarring [11]. In this case series, pterygium excision was performed followed by amniotic membrane transplant (AMT), which was affixed to the corneal and conjunctival defects using ReSure sealant.…”

Section: Introductionmentioning

confidence: 99%

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Minimally Invasive Pterygium Surgery: Sutureless Excision with Amniotic Membrane and Hydrogel Sealant

Bondalapati

Ambati

2016

Case Rep Ophthalmol

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Purpose: To describe a novel technique for sutureless pterygium surgery using ReSure® tissue sealant. Methods: In this retrospective observational case series, we describe a modified procedure for pterygium excision followed by amniotic membrane transplant (AMT) adhered to the corneal and conjunctival defects using ReSure tissue sealant. Results: Nine eyes of seven patients (age range: 28-80 years, 4 females and 3 males) underwent pterygium removal with AMT followed by adherence of tissue to the conjunctival edges with ReSure. No issues with transplant dislocation or failure and no intra- or postoperative complications were noted. No recurrences were noted during the follow-up period. Conclusion: ReSure may be considered as a potential sealant to adhere AMT to defective corneal and conjunctival tissues in sutureless pterygium surgery.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Minimally Invasive Pterygium Surgery: Sutureless Excision with Amniotic Membrane and Hydrogel Sealant

Bondalapati

Ambati

2016

Case Rep Ophthalmol

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“…The liquid hydrogel compound is administered (painted) over the wound, and polymerizes fast (in approximately half a minute) into a soft form that adheres to the ocular surface, forming a bandage that leads to a watertight seal. Two such ocular tissue adhesive products are the ReSure (Ocular Therapeutix, Inc., Bedford, MA) [21] and the OcuSeal (BD Medical, Waltham, MA) [22].…”

Section: Discussionmentioning

confidence: 99%

Untitled

2016

JOJO

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To evaluate clinical safety and efficacy of a novel use of an ocular tissue adhesive in Descemet's Stripping (Automated) Endothelial Keratoplasty (DSAEK). Methods35 consecutive DSAEK cases were evaluated retrospectively. In group-A (n A =15) the tissue adhesive (Re Sure Adherent Ocular Bandage, Ocular Therapeutix, Inc., Bedford, MA) had been used, prior to placement of one suture, while in group-B (n B =20), only nylon sutures were used for the closure of corneal incisions. Peri-operative complications were noted. Visual Acuity, refraction and topographic cylinder, Intraocular Pressure (IOP), and endothelial cell counts (ECC) were monitored long-term for up to two years. ResultsFollow-up time was 10.5±8.5 (8 to 29) months. No case from group-A required any additional air insertion following the tissue adhesive application and no case required additional intra operative surgical manipulation for further graft centration. In group-B eighteen (out of twenty) cases required intra-operative supplemental air insertion, and four of those intra-operative repositioning of the graft. The differences in visual acuity and IOP were not statistically significant; ECC change of -16% in group-A vs. -21% was noted in group-B (statistically significant, p =0.03). Hyperopic shift was noted in both groups; cylinder reduction was noted, too, with group-A performing better. ConclusionsTissue adhesive may be a valuable adjunct in clear-cornea DSEAK by stabilizing the potential of air escape from the main incision inadvertently occurring during suture placement.

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“…It has been used to seal limbal and clear corneal cataract wounds and to seal fornixbased conjunctival flaps in trabeculectomies and has also been used in pterygium surgery. 5 A PEG hydrogel (Resure Sealant, Ocular Therapeutix, Inc.) recently received approval from the U.S. Food and Drug Administration (FDA) for the indication of sealing corneal incisions smaller than 3.5 mm in cataract surgery. A Maintenance of an air bubble in the anterior chamber in the first hours after Descemet-stripping endothelial keratoplasty (DSEK) is crucial to ensure adhesion of the Descemet membrane/endothelial tissue to the recipient stromal bed.…”

Section: Online Videomentioning

confidence: 99%

Endothelial keratoplasty combined with cataract surgery or alone using polyethylene glycol hydrogel sealant for closure of corneal incisions

Spierer

O’Brien

2015

Journal of Cataract and Refractive Surgery

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Pterygium Removal Using a Polyethylene Glycol Hydrogel Adherent Ocular Bandage

Abstract: This hydrogel polymer seems to cause prolonged inflammation and resultant scarring when used over extended areas of Tenons, and it has no role in reducing pain after pterygium surgery.

Cited by 3 publications

References 9 publications

Minimally Invasive Pterygium Surgery: Sutureless Excision with Amniotic Membrane and Hydrogel Sealant

Minimally Invasive Pterygium Surgery: Sutureless Excision with Amniotic Membrane and Hydrogel Sealant

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Endothelial keratoplasty combined with cataract surgery or alone using polyethylene glycol hydrogel sealant for closure of corneal incisions

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