Pterospartum tridentatum, Gomphrena globosa and Cymbopogon citratus: A phytochemical study focused on antioxidant compounds

Roriz, Custódio Lobo; Barros, Lillian; Carvalho, Ana María; Santos‐Buelga, Celestino; Ferreira, Isabel C.F.R.

doi:10.1016/j.foodres.2014.04.036

Cited by 100 publications

(99 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The identification of these compounds was previously performed by authors (Roriz et al, 2014) and confirmed in this study. Four betacyanin compounds were found: gomphrenin II (P1), gomphrenin III (P2), isogomphrenin II (P3) and isogomphrenin III (P4).…”

Section: Betacyanins Analysis and Quantificationsupporting

confidence: 76%

Modern extraction techniques optimized to extract betacyanins from Gomphrena globosa L.

Roriz

Barros

Prieto

et al. 2017

Industrial Crops and Products

Self Cite

View full text Add to dashboard Cite

A B S T R A C TGomphrena globosa L. is a source of betacyanins, molecules with high colorant power. In order to replace conventional extraction techniques, microwave (MAE) and ultrasound assisted extraction (UAE) processes were optimized by the response surface methodology (RSM) to maximize the recovery of betacyanins from G. globosa. A five-level full factorial design of 24 combinations and 4 replicates was implemented for MAE and UAE. The optimum processing conditions for MAE (t = 8 min; T = 60°C; Et = 0%; and S/L = 5 g/L) conducted to an extraction yield of 39.6 ± 1.8 mg/g dry weight, while for UAE (t = 22 min; P = 500%; Et = 0%; and S/ L = 5 g/L) a value of 46.9 ± 4.8 mg/g was achieved, validating the UAE more suitable to obtain the target compounds. This technique can provide extracts rich in betacyanins and with high potential to be used as natural colorants.

show abstract

Section: Betacyanins Analysis and Quantificationsupporting

confidence: 76%

Modern extraction techniques optimized to extract betacyanins from Gomphrena globosa L.

Roriz

Barros

Prieto

et al. 2017

Industrial Crops and Products

Self Cite

View full text Add to dashboard Cite

show abstract

“…16 Plants of this family are particularly predominant in South America, consisting of approximately 120 species, which are employed in folk medicine in the treatment of several diseases due to their biological activities, including antimicrobial, 17 antioxidant, cytotoxic, 18 and hypotensive activities, 19 and they also possess nutritive value. 20 Recent studies have focused mainly on the most common cultivar, purple globe amaranth, dealing with its phytochemical composition, 20,21 antimicrobial, antioxidant and cytotoxic activities, and cardiovascular effects, 18,22,23 as well as its medicinal benefits. 24 Nevertheless, to the best of our knowledge, other Gomphrena species are still poorly or not studied and, since the consumption data indicate that these plants are widely employed around the world for various purposes, especially their traditional use as infusions in order to treat throat disorders, hence it seems of great interest to explore their bioactive potential.…”

Section: 15mentioning

confidence: 99%

“…21 MS detection was performed in an API 3200 Qtrap (Applied Biosystems, Darmstadt, Germany) equipped with an ESI source and a triple quadrupole-ion trap mass analyser that was controlled by the Analyst 5.1 software. Zero grade air served as the nebulizer gas (30 psi) and turbo gas was used for solvent drying (400°C, 40 psi).…”

Section: Organic Acidsmentioning

confidence: 99%

“…and white (Gomphrena globosa var. albiflora) globe amaranth, fourteen of which had been already reported in inflorescences of purple globe amaranth (Gomphrena globosa L.) previously analyzed in our laboratory, 21 so that the same identities have been assumed. The remaining six compounds (i.e., 1, 5, 8, 15, 16 and 17 in Table 2) have been assigned based on their mass Table 3 Retention time (Rt), wavelengths of maximum absorption in the visible region (λ max ), mass spectral data, identification and quantification of phenolic compounds in the red variety of globe amaranth (mean ± SD) Peak Rt (min) − at m/z 563) could correspond to a kaempferol derivative bearing pentosyl and rhamnosyl moieties.…”

Section: Composition In Phenolic Compoundsmentioning

confidence: 99%

See 1 more Smart Citation

A comparison of the bioactivity and phytochemical profile of three different cultivars of globe amaranth: red, white, and pink

et al. 2016

Self Cite

View full text Add to dashboard Cite

aThe phytochemical profiles and bioactivities of red, white and pink globe amaranth (Gomphrena haageana K., Gomphrena globosa var. albiflora and Gomphrena sp., respectively), much less studied than the purple species (G. globosa L.), were compared. The chemical characterization of the samples included the analysis of macronutrients and individual profiles of sugars, organic acids, fatty acids, tocopherols, and phenolic compounds. Their bioactivity was evaluated by determining the antioxidant and anti-inflammatory activities; the absence of cytotoxicity was also determined. Red and pink samples showed the highest sugar content. Otherwise, the white sample gave the highest level of organic acids, and together with the pink one showed the highest tocopherol and PUFA levels. Quercetin-3-O-rutinoside was the major flavonol in white and pink samples, whereas a tetrahydroxy-methylenedioxyflavone was the major compound in the red variety, which revealed a different phenolic profile. The pink globe amaranth hydromethanolic extract revealed the highest antioxidant activity, followed by those of red and white samples.The anti-inflammatory activity was more relevant in red and pink varieties. None of the samples presented toxicity in liver cells. Overall, these samples can be used in bioactive formulations against inflammatory processes and in free radical production.

show abstract

“…Studies previously conducted demonstrated its hypoglycemic, hipolypidemic, anxiolytic, sedative, antioxidant and anti-inflammatory effects [1][2][3][4][5]. Some researchers have studied diverse-origin samples of lemongrass regarding their phenolic composition and antioxidant and anti-inflammatory properties [6][7][8][9]. In the past years, the phenolic composition of lemongrass infusion was described: 3-feroylquinic acid, neochlorogenic acid, chlorogenic acid, p-coumaric acid, carlinoside, isoschaftoside, isoorientin, cynaroside, veronicastroside, luteolin 7-O-neohesperidoside, kurilensin A and cassiaoccidentalin B [10].…”

Section: Introductionmentioning

confidence: 99%

Pharmacokinetics of Cymbopogon Citratus Infusion in Rats after Single Oral Dose Administration

Costa¹,

Fortuna²,

Gonçalves³

et al. 2017

SOJPPS

View full text Add to dashboard Cite

Cymbopogon citratus, commonly known as lemongrass, is a tropical herb used in worldwide traditional medicine for centuries. Studies previously conducted by our team demonstrated its antioxidant and anti-inflammatory effects, and recently, the antiinflammatory potential was also observed in vivo. However, little is known about its pharmacokinetics. The current study aimed at obtaining, for the first time, the pharmacokinetic profile of lemongrass infusion after a single dose oral administration to rats.All in vivo experimental procedures were approved by the Portuguese Veterinary General Division. Male Wistar rats were administered with a single oral dose of lemongrass infusion (68.24 mg/kg) and aliquots of plasma were collected at 0.5, 1, 1.5, 2, 4, 8, 12 and 24 h post-dosing. Liver and kidney samples were collected at 1, 2, 4, 8 and 24 h post-dosing. Plasma and tissues homogenates were processed and luteolin (LUT), luteolin 7-O-glucuronide (L7G), chrysoeriol (CHR), diosmetin (DIO) and luteolin 3'-O-sulphate (L3'S) were quantified employing a RP-HPLC-DAD method. The mean concentration-time profiles obtained were analyzed by a noncompartmental pharmacokinetic analysis using the WinNonlin ® .The pharmacokinetic studies revealed the presence of LUT, L7G, CHR, DIO and L3'S. L7G and L3'S were rapidly detected, with maximum plasma concentrations at 30 min after oral administrations. The concentration-time profile of liver samples evidenced compounds undetected in plasma: LUT, CHR and DIO. L7G, CHR and L3'S were detected in the liver from the first hour and stayed in the tissue until at least 24h.The kidney concentration-time profile revealed the presence of the same compounds detected in plasma.The pharmacokinetic analysis showed that the compounds present in lemongrass infusion are not present in plasma, liver or kidneys. On the other hand, L7G and L3'S were the major metabolites found in plasma and tissues, suggesting that lemongrass polyphenols are promptly metabolized in vivo and their metabolites may be the ones responsible for the anti-inflammatory activity of C. citratus, when orally administered.

show abstract

Pterospartum tridentatum, Gomphrena globosa and Cymbopogon citratus: A phytochemical study focused on antioxidant compounds

Cited by 100 publications

References 51 publications

Modern extraction techniques optimized to extract betacyanins from Gomphrena globosa L.

Modern extraction techniques optimized to extract betacyanins from Gomphrena globosa L.

A comparison of the bioactivity and phytochemical profile of three different cultivars of globe amaranth: red, white, and pink

Pharmacokinetics of Cymbopogon Citratus Infusion in Rats after Single Oral Dose Administration

Contact Info

Product

Resources

About